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Analysis of Mass Fragmentation Patte...

O'Neill, Teresa.

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Analysis of Mass Fragmentation Patterns using DART-MS and GCMS for Drugs of Abuse.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Analysis of Mass Fragmentation Patterns using DART-MS and GCMS for Drugs of Abuse./
Author:	O'Neill, Teresa.
Description:	46 p.
Notes:	Source: Masters Abstracts International, Volume: 53-06.
Contained By:	Masters Abstracts International53-06(E).
Subject:	Analytical chemistry. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1565144
ISBN:	9781321193695

Analysis of Mass Fragmentation Patterns using DART-MS and GCMS for Drugs of Abuse.
O'Neill, Teresa.

Analysis of Mass Fragmentation Patterns using DART-MS and GCMS for Drugs of Abuse. - 46 p.

Source: Masters Abstracts International, Volume: 53-06.

Thesis (M.S.)--State University of New York at Albany, 2014.

This item must not be sold to any third party vendors.

Drugs of abuse have been a major problem for law enforcement departments. The structures of the drugs, as well as the ever changing trends in abuse, make it difficult and time consuming to analyze using modern techniques such as GC-MS. DART-MS is a rapid technique that requires no pre-treatment or re-concentration to analyze a sample. Samples of amphetamines, cathinones and cannabinoids were analyzed using DART-MS and GC-MS in order to provide fragment patterns that would make it easier to identify an unknown drug. Using DART-MS, isomers can be differentiated as well as identified rapidly, which is an advantage over GC-MS. Over 70 samples were analyzed and the mass fragment patterns were tabulated with the fragment loss. This led to some consistencies in the fragments between samples, such as a loss of water or an aromatic ring that will be the foundation work in prediction of unknown drugs of abuse.

ISBN: 9781321193695Subjects--Topical Terms:

3168300
Analytical chemistry.

Analysis of Mass Fragmentation Patterns using DART-MS and GCMS for Drugs of Abuse.
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245 1 0 $a Analysis of Mass Fragmentation Patterns using DART-MS and GCMS for Drugs of Abuse.
300 $a 46 p.
500 $a Source: Masters Abstracts International, Volume: 53-06.
500 $a Adviser: Jason Shepard.
502 $a Thesis (M.S.)--State University of New York at Albany, 2014.
506 $a This item must not be sold to any third party vendors.
520 $a Drugs of abuse have been a major problem for law enforcement departments. The structures of the drugs, as well as the ever changing trends in abuse, make it difficult and time consuming to analyze using modern techniques such as GC-MS. DART-MS is a rapid technique that requires no pre-treatment or re-concentration to analyze a sample. Samples of amphetamines, cathinones and cannabinoids were analyzed using DART-MS and GC-MS in order to provide fragment patterns that would make it easier to identify an unknown drug. Using DART-MS, isomers can be differentiated as well as identified rapidly, which is an advantage over GC-MS. Over 70 samples were analyzed and the mass fragment patterns were tabulated with the fragment loss. This led to some consistencies in the fragments between samples, such as a loss of water or an aromatic ring that will be the foundation work in prediction of unknown drugs of abuse.
590 $a School code: 0668.
650 4 $a Analytical chemistry. $3 3168300
650 4 $a Criminology. $3 533274
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773 0 $t Masters Abstracts International $g 53-06(E).
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