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Preclinical drug development

Rogge, Mark C.

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Preclinical drug development

Record Type:	Electronic resources : Monograph/item
Title/Author:	Preclinical drug development/ edited by Mark C. Rogge, David R. Taft.
other author:	Rogge, Mark C.
Published:	New York :Informa Healthcare, : c2010.,
Description:	viii, 359 p., [8] p. of plates :ill. (some col.).
[NT 15003449]:	1. The scope of preclinical drug development : an introduction and framework / Mark C. Rogge -- 2. Lead molecule selection : pharmaceutical profiling and toxicity assessments / P.L. Bullock -- 3. Interspecies differences in physiology and pharmacology : extrapolating preclinical data to human populations / M.N. Martinez -- 4. Pharmacokinetics/ADME of small molecules / A.D. Ajavon and David R. Taft -- 5. Pharmacokinetics/ADME of large molecules / R. Braeckman -- 6. Preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development / P.L. Bonate and P. Vicini -- 7. Formulation and production strategies for enhancing bioavailability of poorly absorbed drugs / A.B. Watts and R.O. Williams III -- 8. Transporters involved in drug disposition, toxicity, and efficacy / C.Q. Xia and G.T. Miwa -- 9. Toxicity evaluations, ICH guidelines, and current practice / J.L. Larson -- 10. Application of pathology in safety assessment / Robert A. Ettlin and David E. Prentice -- 11. Utilizing the preclinical database to support clinical drug development / H. Lee.
Subject:	Drug development. -
Online resource:	http://marc.crcnetbase.com/isbn/9781420084733Distributed by publisher. Purchase or institutional license may be required for access.
ISBN:	9781420084733 (ebook : PDF)

Preclinical drug development
Preclinical drug development[electronic resource] /edited by Mark C. Rogge, David R. Taft. - 2nd ed. - New York :Informa Healthcare,c2010. - viii, 359 p., [8] p. of plates :ill. (some col.). - Drugs and the pharmaceutical sciences ;187. - Drugs and the pharmaceutical sciences ;v. 183-184.

Includes bibliographical references and index.

1. The scope of preclinical drug development : an introduction and framework / Mark C. Rogge -- 2. Lead molecule selection : pharmaceutical profiling and toxicity assessments / P.L. Bullock -- 3. Interspecies differences in physiology and pharmacology : extrapolating preclinical data to human populations / M.N. Martinez -- 4. Pharmacokinetics/ADME of small molecules / A.D. Ajavon and David R. Taft -- 5. Pharmacokinetics/ADME of large molecules / R. Braeckman -- 6. Preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development / P.L. Bonate and P. Vicini -- 7. Formulation and production strategies for enhancing bioavailability of poorly absorbed drugs / A.B. Watts and R.O. Williams III -- 8. Transporters involved in drug disposition, toxicity, and efficacy / C.Q. Xia and G.T. Miwa -- 9. Toxicity evaluations, ICH guidelines, and current practice / J.L. Larson -- 10. Application of pathology in safety assessment / Robert A. Ettlin and David E. Prentice -- 11. Utilizing the preclinical database to support clinical drug development / H. Lee.

Mode of access: World Wide Web.

ISBN: 9781420084733 (ebook : PDF)Subjects--Topical Terms:

716904
Drug development.
Index Terms--Genre/Form:

542853
Electronic books.

Preclinical drug development
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007 cr||||
008 150804s2010 nyuaf sb 001 0 eng d
020 $a 9781420084733 (ebook : PDF)
035 $a CRC00HE8472PDF
040 $a FlBoTFG $c FlBoTFG
090 $a RM301.25 $b .P745 2010
092 $a 615.19 $b P923
245 0 0 $a Preclinical drug development $h [electronic resource] / $c edited by Mark C. Rogge, David R. Taft.
250 $a 2nd ed.
260 $a New York : $b Informa Healthcare, $c c2010.
300 $a viii, 359 p., [8] p. of plates : $b ill. (some col.).
490 1 $a Drugs and the pharmaceutical sciences ; $v 187
504 $a Includes bibliographical references and index.
505 0 $a 1. The scope of preclinical drug development : an introduction and framework / Mark C. Rogge -- 2. Lead molecule selection : pharmaceutical profiling and toxicity assessments / P.L. Bullock -- 3. Interspecies differences in physiology and pharmacology : extrapolating preclinical data to human populations / M.N. Martinez -- 4. Pharmacokinetics/ADME of small molecules / A.D. Ajavon and David R. Taft -- 5. Pharmacokinetics/ADME of large molecules / R. Braeckman -- 6. Preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development / P.L. Bonate and P. Vicini -- 7. Formulation and production strategies for enhancing bioavailability of poorly absorbed drugs / A.B. Watts and R.O. Williams III -- 8. Transporters involved in drug disposition, toxicity, and efficacy / C.Q. Xia and G.T. Miwa -- 9. Toxicity evaluations, ICH guidelines, and current practice / J.L. Larson -- 10. Application of pathology in safety assessment / Robert A. Ettlin and David E. Prentice -- 11. Utilizing the preclinical database to support clinical drug development / H. Lee.
530 $a Also available in print edition.
538 $a Mode of access: World Wide Web.
650 0 $a Drug development. $3 716904
655 7 $a Electronic books. $2 lcsh $3 542853
700 1 $a Rogge, Mark C. $3 916384
700 1 $a Taft, David R. $3 916385
776 1 $z 9781420084726 (hardcover : alk. paper) $z 1420084720 (hardcover : alk. paper)
830 0 $a Drugs and the pharmaceutical sciences ; $v v. 183-184 $3 1359366
856 4 0 $u http://marc.crcnetbase.com/isbn/9781420084733 $q application/PDF $z Distributed by publisher. Purchase or institutional license may be required for access.