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Endocrine response to acute resistan...

Pham, Hoang.

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Endocrine response to acute resistance exercise in lean versus obese college-aged males.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Endocrine response to acute resistance exercise in lean versus obese college-aged males./
Author:	Pham, Hoang.
Description:	85 p.
Notes:	Source: Masters Abstracts International, Volume: 52-03.
Contained By:	Masters Abstracts International52-03(E).
Subject:	Health Sciences, Recreation. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1523974
ISBN:	9781303473272

Endocrine response to acute resistance exercise in lean versus obese college-aged males.
Pham, Hoang.

Endocrine response to acute resistance exercise in lean versus obese college-aged males. - 85 p.

Source: Masters Abstracts International, Volume: 52-03.

Thesis (M.S.)--California State University, Fullerton, 2013.

Obesity has been shown to blunt the growth hormone (GH) response to resistance exercise (RE), but the effects of excess adiposity on the insulin-like growth factor 1 (IGF-1) and testosterone response remain unclear. The purpose of this study was to examine the effects of adiposity on the RE-associated GH, IGF-1, and testosterone responses. Participants were ten healthy obese males (body fat percentage [BF%]> 30%), and ten age-, and physical activity-matched lean males (BF% < 25%). The moderate-intensity RE protocol consisted of six sets of ten repetitions per leg of stepping onto an elevated platform (20% of participant's height [cm]) while wearing a weighted-vest (50% of participant's lean mass [kg]). Pre-, immediately post- (IP), 15 minutes post- (+15), 30 minutes post- (+30), and 60 minutes post-exercise (+60) blood samples were collected. There was no significant group by time interaction for GH (p = 0.869), but obese males' mean GH value was significantly lower than lean males' value (2.100 +/- 1.600 vs. 0.818 +/- 0.833 ng/mL, respectively, p = 0.019). There was also a significant time effect (p = 0.001). There was an increase in GH value at IP compared to pre- which remained elevated at +15 and +30 (p < 0.050 for all). Furthermore, obese males' mean IGF-1 value was lower than lean males' value (117.214 +/- 46.871 vs. 162.191 +/- 38.562 ng/ml, respectively). Both groups demonstrated an increase in IGF-1 values at IP compared to pre. There was a significant group by time interaction for testosterone (p = 0.015). Obese male's mean testosterone value was significantly lower than lean males' value (2.250 +/- 1.060 vs. 5.716 +/- 1.640 ng/ml, respectively, p < 0.001). Only lean males' IP value was significantly higher than the pre-exercise value (p = 0.017). There were no RE-associated changes in testosterone values in obese males (p > 0.050 for all time points compared to pre). In addition, lean pre, IP, +15, +30 and +60 values were significantly higher than obese values for the same time points (p < 0.050 for all comparisons). These findings confirm that obesity alters the function of the GH/IGF-1 axis and demonstrate that obesity also alters the release of testosterone in response to RE in young healthy males.

ISBN: 9781303473272Subjects--Topical Terms:

1018003
Health Sciences, Recreation.

Endocrine response to acute resistance exercise in lean versus obese college-aged males.
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100 1 $a Pham, Hoang. $3 784005
245 1 0 $a Endocrine response to acute resistance exercise in lean versus obese college-aged males.
300 $a 85 p.
500 $a Source: Masters Abstracts International, Volume: 52-03.
500 $a Adviser: Daniela A. Rubin.
502 $a Thesis (M.S.)--California State University, Fullerton, 2013.
520 $a Obesity has been shown to blunt the growth hormone (GH) response to resistance exercise (RE), but the effects of excess adiposity on the insulin-like growth factor 1 (IGF-1) and testosterone response remain unclear. The purpose of this study was to examine the effects of adiposity on the RE-associated GH, IGF-1, and testosterone responses. Participants were ten healthy obese males (body fat percentage [BF%]> 30%), and ten age-, and physical activity-matched lean males (BF% < 25%). The moderate-intensity RE protocol consisted of six sets of ten repetitions per leg of stepping onto an elevated platform (20% of participant's height [cm]) while wearing a weighted-vest (50% of participant's lean mass [kg]). Pre-, immediately post- (IP), 15 minutes post- (+15), 30 minutes post- (+30), and 60 minutes post-exercise (+60) blood samples were collected. There was no significant group by time interaction for GH (p = 0.869), but obese males' mean GH value was significantly lower than lean males' value (2.100 +/- 1.600 vs. 0.818 +/- 0.833 ng/mL, respectively, p = 0.019). There was also a significant time effect (p = 0.001). There was an increase in GH value at IP compared to pre- which remained elevated at +15 and +30 (p < 0.050 for all). Furthermore, obese males' mean IGF-1 value was lower than lean males' value (117.214 +/- 46.871 vs. 162.191 +/- 38.562 ng/ml, respectively). Both groups demonstrated an increase in IGF-1 values at IP compared to pre. There was a significant group by time interaction for testosterone (p = 0.015). Obese male's mean testosterone value was significantly lower than lean males' value (2.250 +/- 1.060 vs. 5.716 +/- 1.640 ng/ml, respectively, p < 0.001). Only lean males' IP value was significantly higher than the pre-exercise value (p = 0.017). There were no RE-associated changes in testosterone values in obese males (p > 0.050 for all time points compared to pre). In addition, lean pre, IP, +15, +30 and +60 values were significantly higher than obese values for the same time points (p < 0.050 for all comparisons). These findings confirm that obesity alters the function of the GH/IGF-1 axis and demonstrate that obesity also alters the release of testosterone in response to RE in young healthy males.
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650 4 $a Health Sciences, Medicine and Surgery. $3 1017756
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