東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Pharmacological modulation of muscle...

Awadalla, Nancy Amin.

FindBook

Google Book

Amazon

博客來

Pharmacological modulation of muscle-derived stem cells for the repair of ischemic and/or necrotic skeletal muscle.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Pharmacological modulation of muscle-derived stem cells for the repair of ischemic and/or necrotic skeletal muscle./
作者:	Awadalla, Nancy Amin.
面頁冊數:	69 p.
附註:	Source: Masters Abstracts International, Volume: 52-01.
Contained By:	Masters Abstracts International52-01(E).
標題:	Biology, Cell. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1523469
ISBN:	9781303227400

Pharmacological modulation of muscle-derived stem cells for the repair of ischemic and/or necrotic skeletal muscle.
Awadalla, Nancy Amin.

Pharmacological modulation of muscle-derived stem cells for the repair of ischemic and/or necrotic skeletal muscle. - 69 p.

Source: Masters Abstracts International, Volume: 52-01.

Thesis (M.S.)--California State University, Dominguez Hills, 2013.

Critical limb ischemia and Duchene muscular dystrophy are two devastating diseases that eventually result in necrosis and ischemia of skeletal muscle. Minorities, particularly African American women, are at a higher risk for critical limb ischemia for reasons unrelated to social status. The amputation and mortality rate of this disease are substantial. Duchene muscular dystrophy, however, is an X-linked recessive genetic disorder that affects young boys that eventually leads to their death in their early twenties. Ongoing clinical trials are using bone marrow cells and endometrial regenerative cells as a means of stimulating angiogenesis; however, efficiency of using these cells to repair necrotic myofibers is unknown. This study shows that pharmacological modulation of muscle-derived stem cells implanted into the gastrocnemius of an ischemic or dystrophic mouse model may in some cases stimulate angiogenesis and early muscle repair, as well as reduce fibrosis, but this is presumably counteracted by myostatin over-expression.

ISBN: 9781303227400Subjects--Topical Terms:

1017686
Biology, Cell.

Pharmacological modulation of muscle-derived stem cells for the repair of ischemic and/or necrotic skeletal muscle.
LDR:01960nam a2200289 4500 001 1965627
005 20141029122139.5
008 150210s2013 ||||||||||||||||| ||eng d
020 $a 9781303227400
035 $a (MiAaPQ)AAI1523469
035 $a AAI1523469
040 $a MiAaPQ $c MiAaPQ
100 1 $a Awadalla, Nancy Amin. $3 2102308
245 1 0 $a Pharmacological modulation of muscle-derived stem cells for the repair of ischemic and/or necrotic skeletal muscle.
300 $a 69 p.
500 $a Source: Masters Abstracts International, Volume: 52-01.
500 $a Adviser: Helen Chun.
502 $a Thesis (M.S.)--California State University, Dominguez Hills, 2013.
520 $a Critical limb ischemia and Duchene muscular dystrophy are two devastating diseases that eventually result in necrosis and ischemia of skeletal muscle. Minorities, particularly African American women, are at a higher risk for critical limb ischemia for reasons unrelated to social status. The amputation and mortality rate of this disease are substantial. Duchene muscular dystrophy, however, is an X-linked recessive genetic disorder that affects young boys that eventually leads to their death in their early twenties. Ongoing clinical trials are using bone marrow cells and endometrial regenerative cells as a means of stimulating angiogenesis; however, efficiency of using these cells to repair necrotic myofibers is unknown. This study shows that pharmacological modulation of muscle-derived stem cells implanted into the gastrocnemius of an ischemic or dystrophic mouse model may in some cases stimulate angiogenesis and early muscle repair, as well as reduce fibrosis, but this is presumably counteracted by myostatin over-expression.
590 $a School code: 0582.
650 4 $a Biology, Cell. $3 1017686
650 4 $a Biology, Molecular. $3 1017719
650 4 $a Health Sciences, General. $3 1017817
690 $a 0379
690 $a 0307
690 $a 0566
710 2 $a California State University, Dominguez Hills. $3 1017917
773 0 $t Masters Abstracts International $g 52-01(E).
790 $a 0582
791 $a M.S.
792 $a 2013
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1523469