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Physiologically-based pharmacokineti...
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Peters, Sheila Annie.
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Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry /
Record Type:
Electronic resources : Monograph/item
Title/Author:
Physiologically-based pharmacokinetic (PBPK) modeling and simulations/ Sheila Annie Peters.
Reminder of title:
principles, methods, and applications in the pharmaceutical industry /
remainder title:
Physiologically based pharmacokinetic modeling and simulations
Author:
Peters, Sheila Annie.
Published:
Hoboken, N.J. :Wiley, : c2012.,
Description:
1 online resource (xvii, 430 p.) :ill.
Notes:
Wiley online library (ebook collection)
[NT 15003449]:
Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.
Subject:
Pharmacokinetics - Mathematical models. -
Online resource:
http://onlinelibrary.wiley.com/book/10.1002/9781118140291
ISBN:
9781118140291 (electronic bk.)
Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry /
Peters, Sheila Annie.
Physiologically-based pharmacokinetic (PBPK) modeling and simulations
principles, methods, and applications in the pharmaceutical industry /[electronic resource] :Physiologically based pharmacokinetic modeling and simulationsSheila Annie Peters. - Hoboken, N.J. :Wiley,c2012. - 1 online resource (xvii, 430 p.) :ill.
Wiley online library (ebook collection)
Includes bibliographical references and index.
Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.
ISBN: 9781118140291 (electronic bk.)
Source: 10.1002/9781118140291Wiley InterSciencehttp://www3.interscience.wiley.comSubjects--Topical Terms:
916739
Pharmacokinetics
--Mathematical models.
LC Class. No.: RM301.5 / .P48 2012eb
Dewey Class. No.: 615/.7
National Library of Medicine Call No.: QV 38
Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry /
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principles, methods, and applications in the pharmaceutical industry /
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Sheila Annie Peters.
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Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.
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http://onlinelibrary.wiley.com/book/10.1002/9781118140291
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EB RM301.5 .P48 2012eb
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Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry /
/ Peters, Sheila Annie. / Wiley, / 2012
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