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Neurobiology of Huntington's disease...

Lo, Donald C.

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Neurobiology of Huntington's disease = applications to drug discovery /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Neurobiology of Huntington's disease/ edited by Donald C. Lo and Robert E. Hughes.
Reminder of title:	applications to drug discovery /
other author:	Lo, Donald C.
Published:	Boca Raton :CRC Press/Taylor & Francis Group, : 2010.,
Description:	1 online resource :ill. (some col.).
Subject:	Huntington's chorea - Pathophysiology. -
Online resource:	http://www.crcnetbase.com/isbn/9780849390005
ISBN:	9781420008258 (e-book : PDF)

Neurobiology of Huntington's disease = applications to drug discovery /
Neurobiology of Huntington's diseaseapplications to drug discovery /[electronic resource] :edited by Donald C. Lo and Robert E. Hughes. - Boca Raton :CRC Press/Taylor & Francis Group,2010. - 1 online resource :ill. (some col.). - Frontiers in neuroscience. - Frontiers in neuroscience (Boca Raton, Fla.).

Includes bibliographical references.

"Neurobiology of Huntington's Disease: Applications to Drug Discovery presents a thorough review of the issues surrounding drug discovery and development for the treatment of this paradigmatic neurodegenerative disease. Drawing on the expertise of key researchers in the field, the book discusses the basic neurobiology of Huntington's disease and how its monogenic nature confers enormous practical advantages for translational research, including the creation of robust experimental tools, models, and assays to facilitate discovery and validation of molecular targets and drug candidates for HD. Written to support future basic research as well as drug development efforts, this volume: covers the latest research approaches in genetics, genomics, and proteomics, including high-throughput and high-content screening; highlights advances in the discovery and development of new drug therapies for neurodegenerative disorders; examines the practical realities of preclinical testing, clinical testing strategies, and, ultimately, clinical usage While the development of effective drug treatments for Huntington's disease continues to be tremendously challenging, a highly interactive and cooperative community of researchers and clinical investigators now brings us to the threshold of potential breakthroughs in the quest for therapeutic agents. The impressive array of drug discovery resources outlined in the text holds much promise for treating this devastating disease, providing hope to long-suffering Huntington's disease patients and their families."--Publisher's description.

ISBN: 9781420008258 (e-book : PDF)Subjects--Topical Terms:

2017584
Huntington's chorea
--Pathophysiology.Index Terms--Genre/Form:

542853
Electronic books.

LC Class. No.: RC394.H85 / N48 2010

Dewey Class. No.: 616.851 / N494

National Library of Medicine Call No.: WL 390

Neurobiology of Huntington's disease = applications to drug discovery /
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020 $a 1420008250 (e-book : PDF)
020 $z 9780849390005 (hardcover : alk. paper)
020 $z 0849390001 (hardcover : alk. paper)
035 $a ocn677994381
035 $a 1901858
040 $a FlBoTFG $b eng $c PUL $d MMU $d OCLCQ
050 4 $a RC394.H85 $b N48 2010
060 4 $a WL 390
082 0 4 $a 616.851 $b N494
245 0 0 $a Neurobiology of Huntington's disease $h [electronic resource] : $b applications to drug discovery / $c edited by Donald C. Lo and Robert E. Hughes.
260 $a Boca Raton : $b CRC Press/Taylor & Francis Group, $c 2010.
300 $a 1 online resource : $b ill. (some col.).
490 1 $a Frontiers in neuroscience
504 $a Includes bibliographical references.
520 $a "Neurobiology of Huntington's Disease: Applications to Drug Discovery presents a thorough review of the issues surrounding drug discovery and development for the treatment of this paradigmatic neurodegenerative disease. Drawing on the expertise of key researchers in the field, the book discusses the basic neurobiology of Huntington's disease and how its monogenic nature confers enormous practical advantages for translational research, including the creation of robust experimental tools, models, and assays to facilitate discovery and validation of molecular targets and drug candidates for HD. Written to support future basic research as well as drug development efforts, this volume: covers the latest research approaches in genetics, genomics, and proteomics, including high-throughput and high-content screening; highlights advances in the discovery and development of new drug therapies for neurodegenerative disorders; examines the practical realities of preclinical testing, clinical testing strategies, and, ultimately, clinical usage While the development of effective drug treatments for Huntington's disease continues to be tremendously challenging, a highly interactive and cooperative community of researchers and clinical investigators now brings us to the threshold of potential breakthroughs in the quest for therapeutic agents. The impressive array of drug discovery resources outlined in the text holds much promise for treating this devastating disease, providing hope to long-suffering Huntington's disease patients and their families."--Publisher's description.
588 $a Description based on print version record.
650 0 $a Huntington's chorea $x Pathophysiology. $3 2017584
650 0 $a Huntington's chorea $x Molecular aspects. $3 2017585
650 0 $a Neuropharmacology. $3 588720
650 1 2 $a Huntington Disease $x physiopathology. $3 2017586
650 2 2 $a Drug Discovery $x methods. $3 1305509
650 2 2 $a Huntington Disease $x drug therapy. $3 2017587
655 4 $a Electronic books. $2 lcsh $3 542853
700 1 $a Lo, Donald C. $3 2017582
700 1 $a Hughes, Robert E., $c Ph.D. $3 2017583
830 0 $a Frontiers in neuroscience (Boca Raton, Fla.) $3 915689
856 4 0 $u http://www.crcnetbase.com/isbn/9780849390005