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Negative regulation of JAK/STAT pathway.
~
Zhu, Wei.
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Negative regulation of JAK/STAT pathway.
Record Type:
Electronic resources : Monograph/item
Title/Author:
Negative regulation of JAK/STAT pathway./
Author:
Zhu, Wei.
Description:
111 p.
Notes:
Source: Dissertation Abstracts International, Volume: 64-11, Section: B, page: 5373.
Contained By:
Dissertation Abstracts International64-11B.
Subject:
Biology, Molecular. -
Online resource:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3112843
Negative regulation of JAK/STAT pathway.
Zhu, Wei.
Negative regulation of JAK/STAT pathway.
- 111 p.
Source: Dissertation Abstracts International, Volume: 64-11, Section: B, page: 5373.
Thesis (Ph.D.)--University of California, San Diego, 2004.
STAT (signal transducers and activators of transcription) proteins are a family of latent cytoplasmic transcription factors that are activated by a large number of extracellular signals such as cytokines and growth factors.Subjects--Topical Terms:
1017719
Biology, Molecular.
Negative regulation of JAK/STAT pathway.
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Negative regulation of JAK/STAT pathway.
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Source: Dissertation Abstracts International, Volume: 64-11, Section: B, page: 5373.
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Chair: Michael David.
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Thesis (Ph.D.)--University of California, San Diego, 2004.
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STAT (signal transducers and activators of transcription) proteins are a family of latent cytoplasmic transcription factors that are activated by a large number of extracellular signals such as cytokines and growth factors.
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Transcriptional induction by interferons requires the tyrosine and serine phosphorylation of the STAT proteins. For STAT1, arginine methylation at the amino-terminus is also required for its optimal transcriptional activity. Tyrosine dephosphory
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We also demonstrate here that the small dual-specificity phosphatase, VHR selectively tyrosine dephosphorylates another member of the STAT family, STAT5, leading to the subsequent inhibition of STAT5 transcriptional activity and the transcriptio
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3112843
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