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Effects of two resistance training p...

Maddalozzo, Gianni F.

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Effects of two resistance training protocols on insulin-like growth factors, muscle strength and bone mass in older adults.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Effects of two resistance training protocols on insulin-like growth factors, muscle strength and bone mass in older adults./
Author:	Maddalozzo, Gianni F.
Description:	132 p.
Notes:	Source: Dissertation Abstracts International, Volume: 59-07, Section: B, page: 3388.
Contained By:	Dissertation Abstracts International59-07B.
Subject:	Health Sciences, Recreation. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9842464
ISBN:	0591967391

Effects of two resistance training protocols on insulin-like growth factors, muscle strength and bone mass in older adults.
Maddalozzo, Gianni F.

Effects of two resistance training protocols on insulin-like growth factors, muscle strength and bone mass in older adults. - 132 p.

Source: Dissertation Abstracts International, Volume: 59-07, Section: B, page: 3388.

Thesis (Ph.D.)--Oregon State University, 1999.

With age, there are marked declines in bone mineral density (BMD), lean mass (LM), muscular strength, and diminished anabolic hormones, specifically growth hormone (GH) and insulin-like growth factor-I (IGF-I). We compared the effects of a moderate-intensity seated resistance training program using machine weights, to a high-intensity training program using free-weight exercises on regional and total body BMD, LM, muscular strength and power, and serum levels of IGF-I and IGFBP-3 in healthy older men and women. Twenty-eight healthy men (54.58

ISBN: 0591967391Subjects--Topical Terms:

1018003
Health Sciences, Recreation.

Effects of two resistance training protocols on insulin-like growth factors, muscle strength and bone mass in older adults.
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100 1 $a Maddalozzo, Gianni F. $3 1948314
245 1 0 $a Effects of two resistance training protocols on insulin-like growth factors, muscle strength and bone mass in older adults.
300 $a 132 p.
500 $a Source: Dissertation Abstracts International, Volume: 59-07, Section: B, page: 3388.
500 $a Adviser: Christine M. Snow.
502 $a Thesis (Ph.D.)--Oregon State University, 1999.
520 $a With age, there are marked declines in bone mineral density (BMD), lean mass (LM), muscular strength, and diminished anabolic hormones, specifically growth hormone (GH) and insulin-like growth factor-I (IGF-I). We compared the effects of a moderate-intensity seated resistance training program using machine weights, to a high-intensity training program using free-weight exercises on regional and total body BMD, LM, muscular strength and power, and serum levels of IGF-I and IGFBP-3 in healthy older men and women. Twenty-eight healthy men (54.58 $\ pm $ 3.20 yr.,) and twenty-six healthy non-estrogen replaced women (52.83 $\ pm $ 3.26 yr.,) served as their own control group for 12 weeks, then were randomly assigned to either a moderate (60% of 1 RM) or high (70-90% of 1 RM) intensity resistance training group. Training was conducted 3 days per week for 6-months under the supervision of a personal trainer. Prior to and after the control period and at the conclusion of the 6-month intervention period, BMD at the hip, spine and whole body and body composition were assessed by dual-energy x-ray absorpitometry, muscle strength by isokinetic dynamometry, muscular power by Wingate Anaerobic Power Test, and IGF-I by radioimmunoassay. We report that high intensity, but not moderate intensity resistance training produced regional changes in bone mass at the hip. Specifically, high intensity free weight training produced a significant increase in trochanteric BMD for women (2.0%) and for men (1.3%) and a significant decrease in femoral neck BMD for both men and women (1.8%). No changes were observed in total hip BMD. At the spine, high intensity training resulted in a significant $( p<.05) $ gain in men (1.9%) but not women, whereas, moderate intensity training produced no change at this site. Neither circulating IGF-I nor IGFBP3 were altered by either training regimen, however, both training programs resulted in improvements in peak force, anaerobic power and lean mass $( p<.01{-}.05) $ and were similar in both the high intensity (HIF) and moderate intensity (MIM) groups and were independent of gender. Despite these increases, neither intensity protocol significantly increased serum levels of IGF-I. Results demonstrate that high intensity training produced a shift in mineral at the hip for both men and women, increased spine BMD in men but not women, and maintained whole body BMD in both genders. These improvements were not accompanied by changes in circulating levels of IGF-I, IGFBP3 or IGF-I/IGFBP3. Although resistance training of moderate to high intensity produced similar muscle changes in younger older adults, a higher magnitude is necessary to stimulate osteogenesis. The redistribution at the hip indicates a highly-specific response to mechanical loads at this site. The long-term implication of this response is unclear, but in may confer some protection from trochanteric fractures.
590 $a School code: 0172.
650 4 $a Health Sciences, Recreation. $3 1018003
650 4 $a Health Sciences, Rehabilitation and Therapy. $3 1017926
650 4 $a Gerontology. $3 533633
690 $a 0575
690 $a 0382
690 $a 0351
710 2 0 $a Oregon State University. $3 625720
773 0 $t Dissertation Abstracts International $g 59-07B.
790 1 0 $a Snow, Christine M., $e advisor
790 $a 0172
791 $a Ph.D.
792 $a 1999
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9842464