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Real time in vivo loading in the lum...

Ledet, Eric H.

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Real time in vivo loading in the lumbar spine: A novel approach using an interbody spinal implant.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Real time in vivo loading in the lumbar spine: A novel approach using an interbody spinal implant./
作者:	Ledet, Eric H.
面頁冊數:	148 p.
附註:	Source: Dissertation Abstracts International, Volume: 64-04, Section: B, page: 1813.
Contained By:	Dissertation Abstracts International64-04B.
標題:	Engineering, Biomedical. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3088510

Real time in vivo loading in the lumbar spine: A novel approach using an interbody spinal implant.
Ledet, Eric H.

Real time in vivo loading in the lumbar spine: A novel approach using an interbody spinal implant. - 148 p.

Source: Dissertation Abstracts International, Volume: 64-04, Section: B, page: 1813.

Thesis (Ph.D.)--Rensselaer Polytechnic Institute, 2003.

Degenerative disc disease is a common condition affecting the population of all industrialized nations. There are treatment options for patients suffering from low back pain, yet little is understood about the etiology. To better understand the biomechanics of spinal pathology, indirect methods have been used to describe the mechanical environment <italic>in vivo</italic>. To date, these methods have not been validated by direct experimental measurement, and therefore the <italic>in vivo</italic> mechanical environment has yet to be comprehensively characterized.Subjects--Topical Terms:

1017684
Engineering, Biomedical.

Real time in vivo loading in the lumbar spine: A novel approach using an interbody spinal implant.
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245 1 0 $a Real time in vivo loading in the lumbar spine: A novel approach using an interbody spinal implant.
300 $a 148 p.
500 $a Source: Dissertation Abstracts International, Volume: 64-04, Section: B, page: 1813.
500 $a Adviser: John B. Brunski.
502 $a Thesis (Ph.D.)--Rensselaer Polytechnic Institute, 2003.
520 $a Degenerative disc disease is a common condition affecting the population of all industrialized nations. There are treatment options for patients suffering from low back pain, yet little is understood about the etiology. To better understand the biomechanics of spinal pathology, indirect methods have been used to describe the mechanical environment <italic>in vivo</italic>. To date, these methods have not been validated by direct experimental measurement, and therefore the <italic>in vivo</italic> mechanical environment has yet to be comprehensively characterized.
520 $a The purpose of this research was to: develop a methodology to accurately measure, in real time, the <italic>in vivo</italic> loading in the lumbar spine of the baboon, a semi-upright animal; to determine if the forces developed in the lumbar spine are dependent on activity; and to assess the baboon as an animal model for human lumbar spine research.
520 $a To determine the real time forces in the lumbar spine, an interbody spinal implant was designed and instrumented with strain gages to be used as a load cell. The implant was placed in the lumbar spine of a baboon. Strain data were collected <italic>in vivo</italic> during normal activities and transmitted via a telemetry system. The forces transmitted through the implant were calculated from the measured strain based on pre-calibration of the load cell. Correlations between forces and activities were determined over a six week period.
520 $a Results indicate that the loads developed in the lumbar spine are dependent on activity and posture, and that muscle forces and body weight contribute to the loading. The maximum loads in the lumbar spine exceeded four times body weight. Force data indicate similar trends between the human and baboon lumbar spine.
520 $a The results from this study indicate that it is possible to monitor real time forces developed in the lumbar spine. The results may help to predict the loading on the lumbar spine during everyday activities, which may assist in understanding biomechanics leading to degenerative disc disease. Results also indicate that the baboon may be an appropriate model for study of the human lumbar spine and therefore may provide insights into the causes and treatments for spinal disorders.
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650 4 $a Biology, Animal Physiology. $3 1017835
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773 0 $t Dissertation Abstracts International $g 64-04B.
790 1 0 $a Brunski, John B., $e advisor
790 $a 0185
791 $a Ph.D.
792 $a 2003
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3088510