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Analysis of clinical trials when tre...

McClure, Leslie Ain.

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Analysis of clinical trials when treatments favor different outcomes.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Analysis of clinical trials when treatments favor different outcomes./
Author:	McClure, Leslie Ain.
Description:	123 p.
Notes:	Source: Dissertation Abstracts International, Volume: 65-06, Section: B, page: 2990.
Contained By:	Dissertation Abstracts International65-06B.
Subject:	Statistics. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3137891
ISBN:	0496850611

Analysis of clinical trials when treatments favor different outcomes.
McClure, Leslie Ain.

Analysis of clinical trials when treatments favor different outcomes. - 123 p.

Source: Dissertation Abstracts International, Volume: 65-06, Section: B, page: 2990.

Thesis (Ph.D.)--University of Michigan, 2004.

It is increasingly common in clinical trials to design studies for which more than one primary outcome exists. Methods that exist for more than one outcome are generally concerned with identifying one of two situations: (1) improvement in all ou

ISBN: 0496850611Subjects--Topical Terms:

517247
Statistics.

Analysis of clinical trials when treatments favor different outcomes.
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100 1 $a McClure, Leslie Ain. $3 1930598
245 1 0 $a Analysis of clinical trials when treatments favor different outcomes.
300 $a 123 p.
500 $a Source: Dissertation Abstracts International, Volume: 65-06, Section: B, page: 2990.
500 $a Chair: Morton B. Brown.
502 $a Thesis (Ph.D.)--University of Michigan, 2004.
520 $a It is increasingly common in clinical trials to design studies for which more than one primary outcome exists. Methods that exist for more than one outcome are generally concerned with identifying one of two situations: (1) improvement in all ou
520 $a In the first part of this dissertation, a likelihood ratio approach is developed to test whether or not a treatment difference exists at the end of the study. This method involves simultaneously testing each component of the null hypothesis, whi
520 $a The second part of this dissertation addresses interim analyses of studies with hypotheses similar to the CARE study. Methodology inspired by Spiegelhalter et al.'s (1986) predictive probability approach is developed which involves determining t
590 $a School code: 0127.
650 4 $a Statistics. $3 517247
650 4 $a Health Sciences, Public Health. $3 1017659
650 4 $a Biology, Biostatistics. $3 1018416
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710 2 0 $a University of Michigan. $3 777416
773 0 $t Dissertation Abstracts International $g 65-06B.
790 1 0 $a Brown, Morton B., $e advisor
790 $a 0127
791 $a Ph.D.
792 $a 2004
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