東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Bioavailability of the tea flavonoid...

Vaidyanathan, Jayabharathi.

Linked to FindBook

Google Book

Amazon

博客來

Bioavailability of the tea flavonoids epicatechin and epicatechin gallate: Role of membrane transport and metabolism.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Bioavailability of the tea flavonoids epicatechin and epicatechin gallate: Role of membrane transport and metabolism./
Author:	Vaidyanathan, Jayabharathi.
Description:	157 p.
Notes:	Source: Dissertation Abstracts International, Volume: 64-07, Section: B, page: 3211.
Contained By:	Dissertation Abstracts International64-07B.
Subject:	Health Sciences, Pharmacology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3098199
ISBN:	049645811X

Bioavailability of the tea flavonoids epicatechin and epicatechin gallate: Role of membrane transport and metabolism.
Vaidyanathan, Jayabharathi.

Bioavailability of the tea flavonoids epicatechin and epicatechin gallate: Role of membrane transport and metabolism. - 157 p.

Source: Dissertation Abstracts International, Volume: 64-07, Section: B, page: 3211.

Thesis (Ph.D.)--Medical University of South Carolina, 2003.

Tea flavonoids, including (-)-epicatechin (EC), (-)-epicatechin gallate (ECG), (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin (EGC) have been shown to have chemopreventive activity in cancer. Studies in animals and humans suggest t

ISBN: 049645811XSubjects--Topical Terms:

1017717
Health Sciences, Pharmacology.

Bioavailability of the tea flavonoids epicatechin and epicatechin gallate: Role of membrane transport and metabolism.
LDR:01967nmm 2200313 4500 001 1841968
005 20050916110234.5
008 130614s2003 eng d
020 $a 049645811X
035 $a (UnM)AAI3098199
035 $a AAI3098199
040 $a UnM $c UnM
100 1 $a Vaidyanathan, Jayabharathi. $3 1930245
245 1 0 $a Bioavailability of the tea flavonoids epicatechin and epicatechin gallate: Role of membrane transport and metabolism.
300 $a 157 p.
500 $a Source: Dissertation Abstracts International, Volume: 64-07, Section: B, page: 3211.
500 $a Adviser: Thomas Walle.
502 $a Thesis (Ph.D.)--Medical University of South Carolina, 2003.
520 $a Tea flavonoids, including (-)-epicatechin (EC), (-)-epicatechin gallate (ECG), (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin (EGC) have been shown to have chemopreventive activity in cancer. Studies in animals and humans suggest t
520 $a We used the Caco-2 cell monolayers, a well-established model to study human intestinal absorption together with molecularly-specific HPLC to characterize the transport of EC and ECG. We found that EC showed a direction dependency in transport, w
520 $a In contrast to EC, when cell uptake studies were done using its corresponding gallate ECG, it was very efficiently transported across the apical membrane of the Caco-2 cells by a pH-dependent mechanism presumably by the monocarboxylate transport
520 $a Thus, the work described in this dissertation helps to understand the mechanisms governing the intestinal absorption of dietary catechins. This work has also helped identify the major site of action of these flavonoids. The observations made dem
590 $a School code: 0122.
650 4 $a Health Sciences, Pharmacology. $3 1017717
650 4 $a Chemistry, Pharmaceutical. $3 550957
690 $a 0419
690 $a 0491
710 2 0 $a Medical University of South Carolina. $3 700119
773 0 $t Dissertation Abstracts International $g 64-07B.
790 1 0 $a Walle, Thomas, $e advisor
790 $a 0122
791 $a Ph.D.
792 $a 2003
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3098199