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Examination of the relationship betw...

Malek, Moh H.

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Examination of the relationship between the slow component of oxygen uptake kinetics and plasma ammonia concentrations during cycle ergometer exercise.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Examination of the relationship between the slow component of oxygen uptake kinetics and plasma ammonia concentrations during cycle ergometer exercise./
Author:	Malek, Moh H.
Description:	96 p.
Notes:	Source: Dissertation Abstracts International, Volume: 68-02, Section: B, page: 0926.
Contained By:	Dissertation Abstracts International68-02B.
Subject:	Health Sciences, Recreation. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3252440

Examination of the relationship between the slow component of oxygen uptake kinetics and plasma ammonia concentrations during cycle ergometer exercise.
Malek, Moh H.

Examination of the relationship between the slow component of oxygen uptake kinetics and plasma ammonia concentrations during cycle ergometer exercise. - 96 p.

Source: Dissertation Abstracts International, Volume: 68-02, Section: B, page: 0926.

Thesis (Ph.D.)--The University of Nebraska - Lincoln, 2007.

The purposes of this study were to: (1) compare the patterns of responses for plasma ammonia concentration ([NH3]) during moderate- and heavy intensity cycle ergometry; and (2) examine the relationship between the V&dot;O2 slow component (V&dot;O2SC) and plasma [NH3]. Thirteen healthy, untrained college males who performed less than a total of two hours of aerobic and/or resistance exercise per week visited the laboratory on six separate occasions. The initial visit included a V&dot;O2max test, whereas subsequent visits involved constant power output exercise (7-minutes in duration) at two different intensities [moderate 60%GET = 60% of the gas exchange threshold; and heavy, Delta50% = 50% of the difference between GET and V&dot;O2max)]. Plasma was collected from an antecubital vein prior to the exercise, during the last three minutes of the six minute warm-up, and during each minute of the seven minute constant power output workbout. The time course of changes in plasma [NH3] and V&dot;O2 during the two constant power output exercise intensities (60%GET and Delta50%) were assessed separately using 2 (intensity: 60%GET and Delta50%) x 7 (time: each minute of 7-minute workbout) repeated-measures ANOVAs. When appropriate, Scheffe's post-hoc analyses were used to determine significantly different mean values. In addition, a Pearson's correlation coefficient was calculated to assess the relationship between plasma [NH3] and the amplitude of the V&dot;O2SC for the heavy intensity exercise. For moderate intensity exercise (60%GET), there were no significant differences in the mean normalized plasma [NH3] during the 7-minute workbout. In addition, the mean normalized V&dot;O2 values were not significantly different from each other during the final 5-minutes of the exercise workbout. For heavy intensity exercise (Delta50%), there was a significant increase in the mean normalized plasma [NH3] during the 7-minute workbout. Similarly, the mean normalized V&dot;O 2 response increased significantly during the entire 7-minute workbout. Pearson's correlation coefficient indicated a significant (r = 0.76, p < 0.05) relationship between [NH3]Delta7-3 (the difference in normalized [NH3] between the 7 th- and 3rd-minute ([NH3]Delta7-3 ) of the Delta50% constant power output exercise) and the V&dot;O2SC amplitude. The results indicated that during moderate intensity exercise, the V&dot;O2 response reached a steady-state with no change in plasma [NH3] from baseline values. For the heavy intensity exercise, however, there was a V&dot;O 2SC and plasma [NH3] increased continuously until the end of exercise. These findings suggest a potential relationship between exercise-induced increase in plasma [NH3] and the V&dot;O 2SC during heavy intensity exercise.Subjects--Topical Terms:

1018003
Health Sciences, Recreation.

Examination of the relationship between the slow component of oxygen uptake kinetics and plasma ammonia concentrations during cycle ergometer exercise.
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008 130610s2007 eng d
035 $a (UMI)AAI3252440
035 $a AAI3252440
040 $a UMI $c UMI
100 1 $a Malek, Moh H. $3 1328309
245 1 0 $a Examination of the relationship between the slow component of oxygen uptake kinetics and plasma ammonia concentrations during cycle ergometer exercise.
300 $a 96 p.
500 $a Source: Dissertation Abstracts International, Volume: 68-02, Section: B, page: 0926.
500 $a Adviser: Terry J. Housh.
502 $a Thesis (Ph.D.)--The University of Nebraska - Lincoln, 2007.
520 $a The purposes of this study were to: (1) compare the patterns of responses for plasma ammonia concentration ([NH3]) during moderate- and heavy intensity cycle ergometry; and (2) examine the relationship between the V&dot;O2 slow component (V&dot;O2SC) and plasma [NH3]. Thirteen healthy, untrained college males who performed less than a total of two hours of aerobic and/or resistance exercise per week visited the laboratory on six separate occasions. The initial visit included a V&dot;O2max test, whereas subsequent visits involved constant power output exercise (7-minutes in duration) at two different intensities [moderate 60%GET = 60% of the gas exchange threshold; and heavy, Delta50% = 50% of the difference between GET and V&dot;O2max)]. Plasma was collected from an antecubital vein prior to the exercise, during the last three minutes of the six minute warm-up, and during each minute of the seven minute constant power output workbout. The time course of changes in plasma [NH3] and V&dot;O2 during the two constant power output exercise intensities (60%GET and Delta50%) were assessed separately using 2 (intensity: 60%GET and Delta50%) x 7 (time: each minute of 7-minute workbout) repeated-measures ANOVAs. When appropriate, Scheffe's post-hoc analyses were used to determine significantly different mean values. In addition, a Pearson's correlation coefficient was calculated to assess the relationship between plasma [NH3] and the amplitude of the V&dot;O2SC for the heavy intensity exercise. For moderate intensity exercise (60%GET), there were no significant differences in the mean normalized plasma [NH3] during the 7-minute workbout. In addition, the mean normalized V&dot;O2 values were not significantly different from each other during the final 5-minutes of the exercise workbout. For heavy intensity exercise (Delta50%), there was a significant increase in the mean normalized plasma [NH3] during the 7-minute workbout. Similarly, the mean normalized V&dot;O 2 response increased significantly during the entire 7-minute workbout. Pearson's correlation coefficient indicated a significant (r = 0.76, p < 0.05) relationship between [NH3]Delta7-3 (the difference in normalized [NH3] between the 7 th- and 3rd-minute ([NH3]Delta7-3 ) of the Delta50% constant power output exercise) and the V&dot;O2SC amplitude. The results indicated that during moderate intensity exercise, the V&dot;O2 response reached a steady-state with no change in plasma [NH3] from baseline values. For the heavy intensity exercise, however, there was a V&dot;O 2SC and plasma [NH3] increased continuously until the end of exercise. These findings suggest a potential relationship between exercise-induced increase in plasma [NH3] and the V&dot;O 2SC during heavy intensity exercise.
590 $a School code: 0138.
650 4 $a Health Sciences, Recreation. $3 1018003
650 4 $a Biology, Physiology. $3 1017816
690 $a 0575
690 $a 0719
710 2 0 $a The University of Nebraska - Lincoln. $3 1024939
773 0 $t Dissertation Abstracts International $g 68-02B.
790 1 0 $a Housh, Terry J., $e advisor
790 $a 0138
791 $a Ph.D.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3252440