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Family influence in interest and dec...

Powell, Traci Monee.

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Family influence in interest and decisions regarding BRCA testing.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Family influence in interest and decisions regarding BRCA testing./
Author:	Powell, Traci Monee.
Description:	190 p.
Notes:	Source: Dissertation Abstracts International, Volume: 62-09, Section: B, page: 3896.
Contained By:	Dissertation Abstracts International62-09B.
Subject:	Biology, Genetics. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3026886
ISBN:	9780493383194

Family influence in interest and decisions regarding BRCA testing.
Powell, Traci Monee.

Family influence in interest and decisions regarding BRCA testing. - 190 p.

Source: Dissertation Abstracts International, Volume: 62-09, Section: B, page: 3896.

Thesis (Ph.D.)--Stanford University, 2001.

Family influence and concern about members' breast cancer risk have both been cited as major motivations for women considering undergoing BRCA testing. However, it remains unclear why there is a large discrepancy between high interest in BRCA testing and actual utilization of testing among women at genetic risk. This study aims to identify family response patterns that may affect how an individual perceives and acts upon BRCA testing. If BRCA testing is going to be useful, there is a need to know more about women's perspectives on this issue. This will help to define strategies for clinical intervention. One qualitative interview was conducted with each participant using open-ended questions to explore family cancer experiences and attitudes towards breast cancer and BRCA testing in a sample of 53 adult women. These women were predominantly Caucasian and well-educated. Participants were divided into three groups depending on the number of breast and ovarian cancer cases in their family. The interviews were taped and transcribed verbatim into a qualitative database program. The data was analyzed using grounded theory. There are different levels of interest and non-interest in BRCA testing in women with personal or family history of breast and/or ovarian cancer, regardless of the frequency of cancer cases in that family. Women with a family history of these cancers manage their genetic cancer risk by going through a process which includes developing their risk perception and using various coping mechanisms. Also, a change in family dynamic is occurring simultaneously: individuals develop protective beliefs regarding breast cancer issues, those beliefs become family beliefs, and then family beliefs are passed from one generation to the next. Participants ultimately believed that familial cancer was multi-factorial (a combination of environmental and genetic factors). Participants were more preoccupied with protecting themselves and their families from worry about breast cancer risk than they were about preventing the disease itself. Protection from worry allows them to feel in control of their breast cancer risk. Family members influence each other throughout this process. The most important motivation for those who choose to pursue BRCA testing is concern about personal risk. These women may or may not be motivated by risk for their family or future generations. The most important motivation against BRCA testing is the belief that such testing is not useful for reducing breast cancer risk or preventing the disease. In contrast to existing literature, which shows that health care professionals perceive BRCA testing as being ultimately useful, the results of this study indicate that those at genetic risk are more concerned about eliminating anxiety produced by having a family history of breast cancer. Individual and family protective beliefs are deeply ingrained in a person's breast cancer risk perception. Understanding at-risk individuals and families' perspective on BRCA testing can improve doctor-patient communication and guide public policy issues in informed consent and genetic education. Thus, studies such as this can help improve the clinical use of BRCA testing.

ISBN: 9780493383194Subjects--Topical Terms:

1017730
Biology, Genetics.

Family influence in interest and decisions regarding BRCA testing.
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