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Biological effects of resveratrol on...

Breen, Danna M.

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Biological effects of resveratrol on skeletal muscle cells.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Biological effects of resveratrol on skeletal muscle cells./
Author:	Breen, Danna M.
Description:	213 p.
Notes:	Source: Masters Abstracts International, Volume: 44-04, page: 1736.
Contained By:	Masters Abstracts International44-04.
Subject:	Biology, Cell. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MR10706
ISBN:	9780494107065

Biological effects of resveratrol on skeletal muscle cells.
Breen, Danna M.

Biological effects of resveratrol on skeletal muscle cells. - 213 p.

Source: Masters Abstracts International, Volume: 44-04, page: 1736.

Thesis (M.Sc.)--Brock University (Canada), 2005.

Resveratrol, a polyphenol found in red wine, has been reported to have antithrombotic, antiatherogenic, and anticancer properties both in vitro and in vivo. However, possible antidiabetic properties of resveratrol have not been examined. The objective of this study was to investigate the direct effects of resveratrol on basal and insulin-stimulated glucose uptake and to elucidate its mechanism of action in skeletal muscle cells. In addition, the effects of resveratrol on basal and insulin-stimulated amino acid transport and mitogenesis were also examined.

ISBN: 9780494107065Subjects--Topical Terms:

1017686
Biology, Cell.

Biological effects of resveratrol on skeletal muscle cells.
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020 $a 9780494107065
035 $a (UnM)AAIMR10706
035 $a AAIMR10706
040 $a UnM $c UnM
100 1 $a Breen, Danna M. $3 1919025
245 1 0 $a Biological effects of resveratrol on skeletal muscle cells.
300 $a 213 p.
500 $a Source: Masters Abstracts International, Volume: 44-04, page: 1736.
502 $a Thesis (M.Sc.)--Brock University (Canada), 2005.
520 $a Resveratrol, a polyphenol found in red wine, has been reported to have antithrombotic, antiatherogenic, and anticancer properties both in vitro and in vivo. However, possible antidiabetic properties of resveratrol have not been examined. The objective of this study was to investigate the direct effects of resveratrol on basal and insulin-stimulated glucose uptake and to elucidate its mechanism of action in skeletal muscle cells. In addition, the effects of resveratrol on basal and insulin-stimulated amino acid transport and mitogenesis were also examined.
520 $a Results suggest that resveratrol increases glucose transport in L6 skeletal muscle cells by a mechanism that is independent of insulin and protein synthesis. Resveratrol-stimulated glucose uptake may be PI3K and actin cytoskeleton-dependent and independent of Akt/PKB, PKC, ERK1/2, JNK1/2, p38 MAPK, and GLUT4 translocation. However, unlike glucose transport, resveratrol inhibits both basal and insulin-stimulated amino acid transport and mitogenesis. (Abstract shortened by UMI.)
590 $a School code: 1476.
650 4 $a Biology, Cell. $3 1017686
650 4 $a Biology, Animal Physiology. $3 1017835
690 $a 0379
690 $a 0433
710 2 0 $a Brock University (Canada). $3 1018667
773 0 $t Masters Abstracts International $g 44-04.
790 $a 1476
791 $a M.Sc.
792 $a 2005
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MR10706