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Influence of vitamin D receptor gene...

Harne, Amanda Janel.

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Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training./
Author:	Harne, Amanda Janel.
Description:	97 p.
Notes:	Source: Masters Abstracts International, Volume: 43-03, page: 0776.
Contained By:	Masters Abstracts International43-03.
Subject:	Biology, Genetics. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1423947
ISBN:	9780496128396

Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training.
Harne, Amanda Janel.

Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training. - 97 p.

Source: Masters Abstracts International, Volume: 43-03, page: 0776.

Thesis (M.A.)--University of Maryland, College Park, 2005.

The purpose of the study was to examine the influence of the FokI and BsmI polymorphisms of the vitamin D receptor gene on changes in insulin sensitivity with aerobic exercise training in men and women at increased risk for type 2 diabetes mellitus (T2DM). Subjects were genotyped and underwent oral glucose tolerance tests before and after six months of training. Due to mis-genotyping of the BsmI polymorphism, results for that variant were not reported. There were no significant differences between FokI genotype groups in insulin sensitivity before or after training. However, among subjects who completed training, FF homozygotes had significantly higher baseline fasting glucose and insulin levels than f allele carriers. While the FokI polymorphism does not appear to mediate training-induced changes in indices of glucose and insulin metabolism, it may influence fasting glucose and insulin levels and the development of insulin resistance in individuals at increased risk for T2DM.

ISBN: 9780496128396Subjects--Topical Terms:

1017730
Biology, Genetics.

Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training.
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020 $a 9780496128396
035 $a (UnM)AAI1423947
035 $a AAI1423947
040 $a UnM $c UnM
100 1 $a Harne, Amanda Janel. $3 1915634
245 1 0 $a Influence of vitamin D receptor gene polymorphisms on changes in insulin sensitivity with aerobic exercise training.
300 $a 97 p.
500 $a Source: Masters Abstracts International, Volume: 43-03, page: 0776.
500 $a Chair: James M. Hagberg.
502 $a Thesis (M.A.)--University of Maryland, College Park, 2005.
520 $a The purpose of the study was to examine the influence of the FokI and BsmI polymorphisms of the vitamin D receptor gene on changes in insulin sensitivity with aerobic exercise training in men and women at increased risk for type 2 diabetes mellitus (T2DM). Subjects were genotyped and underwent oral glucose tolerance tests before and after six months of training. Due to mis-genotyping of the BsmI polymorphism, results for that variant were not reported. There were no significant differences between FokI genotype groups in insulin sensitivity before or after training. However, among subjects who completed training, FF homozygotes had significantly higher baseline fasting glucose and insulin levels than f allele carriers. While the FokI polymorphism does not appear to mediate training-induced changes in indices of glucose and insulin metabolism, it may influence fasting glucose and insulin levels and the development of insulin resistance in individuals at increased risk for T2DM.
590 $a School code: 0117.
650 4 $a Biology, Genetics. $3 1017730
690 $a 0369
710 2 0 $a University of Maryland, College Park. $3 657686
773 0 $t Masters Abstracts International $g 43-03.
790 1 0 $a Hagberg, James M., $e advisor
790 $a 0117
791 $a M.A.
792 $a 2005
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1423947