東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Surface interaction, polarization an...

Noto, Mayumi.

Linked to FindBook

Google Book

Amazon

博客來

Surface interaction, polarization and molecular weight effects for a whispering gallery mode sensor.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Surface interaction, polarization and molecular weight effects for a whispering gallery mode sensor./
Author:	Noto, Mayumi.
Description:	102 p.
Notes:	Source: Dissertation Abstracts International, Volume: 66-10, Section: B, page: 5409.
Contained By:	Dissertation Abstracts International66-10B.
Subject:	Chemistry, Organic. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3192917
ISBN:	9780542357794

Surface interaction, polarization and molecular weight effects for a whispering gallery mode sensor.
Noto, Mayumi.

Surface interaction, polarization and molecular weight effects for a whispering gallery mode sensor. - 102 p.

Source: Dissertation Abstracts International, Volume: 66-10, Section: B, page: 5409.

Thesis (Ph.D.)--Polytechnic University, 2005.

In this thesis, we investigate the use of an optical resonance of a microsphere in measuring the thickness and dielectric constant of a bio-nano-layer and in determining the molecular orientation of an adsorbate at the sphere surface. We also establish the molecular weight sensitivity of the resonance frequency shift.

ISBN: 9780542357794Subjects--Topical Terms:

516206
Chemistry, Organic.

Surface interaction, polarization and molecular weight effects for a whispering gallery mode sensor.
LDR:03205nmm 2200337 4500 001 1826665
005 20061218070909.5
008 130610s2005 eng d
020 $a 9780542357794
035 $a (UnM)AAI3192917
035 $a AAI3192917
040 $a UnM $c UnM
100 1 $a Noto, Mayumi. $3 1915622
245 1 0 $a Surface interaction, polarization and molecular weight effects for a whispering gallery mode sensor.
300 $a 102 p.
500 $a Source: Dissertation Abstracts International, Volume: 66-10, Section: B, page: 5409.
500 $a Adviser: Steve Arnold.
502 $a Thesis (Ph.D.)--Polytechnic University, 2005.
520 $a In this thesis, we investigate the use of an optical resonance of a microsphere in measuring the thickness and dielectric constant of a bio-nano-layer and in determining the molecular orientation of an adsorbate at the sphere surface. We also establish the molecular weight sensitivity of the resonance frequency shift.
520 $a The resonances of silica microspheres can be very narrow (i.e. high Quality Factor, Q and as a result are extremely sensitive to dielectric perturbations at the sphere surface. In particular, one may use the shift of the resonant frequency to detect the adsorption of bio-molecules with unprecedented sensitivity.
520 $a This work goes beyond the detection of nanoscopic bio-molecules to the characterization of polymer layers &sim;100 nm in thickness. The possibility of enlarging the scope of the sensor is inspired by first order perturbation theory. The theory reveals that the evanescent field decay length influences resonance shifts and may be used as a nanoscopic ruler. Through this theoretical discussion, the idea of using the two light sources to stimulate resonances in an individual microsphere precipitated. Microsphere Wavelength Multiplexing (MWM) experiments proved the theory to be sound. The measurement of simultaneous shifts of two resonances at widely separated wavelengths allowed us to determine the thickness and the dielectric excess of an important bionanolayer (poly-L-lysine) even though its refractive index only exceeded that of the aqueous buffer solution by 0.0012.
520 $a We revisited protein adsorption and investigated the molecular weight MW sensitivity of the sensor. We found that the resonance shift is proportional to MW1/3. A new theoretical model explains the MW1/3 dependence and concludes that spherical protein covers 34% of the microsphere surface and the effective layer refractive index is 1.39.
520 $a We demonstrate polarization specific stimulation of resonances and measure TE and TM mode shifts by inducing a refractive index change in the medium. NaCl addition experiment confirms TM to TE shift ratio predicted by perturbation theory. The polarization specific measurement is applied to investigate the orientation of phenol molecule at the silica surface.
590 $a School code: 0179.
650 4 $a Chemistry, Organic. $3 516206
650 4 $a Chemistry, Pharmaceutical. $3 550957
650 4 $a Chemistry, Polymer. $3 1018428
690 $a 0490
690 $a 0491
690 $a 0495
710 2 0 $a Polytechnic University. $3 1249856
773 0 $t Dissertation Abstracts International $g 66-10B.
790 1 0 $a Arnold, Steve, $e advisor
790 $a 0179
791 $a Ph.D.
792 $a 2005
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3192917