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Effects of phosphated titanium and e...

Dacy, Justin Anthony.

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Effects of phosphated titanium and enamel matrix derivatives on osteoblast behavior in vitro.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Effects of phosphated titanium and enamel matrix derivatives on osteoblast behavior in vitro./
Author:	Dacy, Justin Anthony.
Description:	66 p.
Notes:	Source: Masters Abstracts International, Volume: 44-04, page: 1804.
Contained By:	Masters Abstracts International44-04.
Subject:	Health Sciences, Dentistry. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1432164
ISBN:	9780542505058

Effects of phosphated titanium and enamel matrix derivatives on osteoblast behavior in vitro.
Dacy, Justin Anthony.

Effects of phosphated titanium and enamel matrix derivatives on osteoblast behavior in vitro. - 66 p.

Source: Masters Abstracts International, Volume: 44-04, page: 1804.

Thesis (M.S.)--The Texas A&M University System Health Science Center, 2006.

The effects of phosphated titanium and enamel matrix derivatives (EMD) were evaluated on osteoblast attachment and function. Primary rat osteoblasts were cultured on phosphated or non-phosphated titanium for 28 days; half the samples received EMD. Analysis was done using TGF-beta1 and IL-1beta ELISAs, scanning electron microscopy and light microscopy. Microscopic evaluation revealed osteoblasts increasing in number on all discs from day 2 to 28. Nodule formation occurred in all groups and when EMD was added numbers increased. Without EMD and mineralizing media, non-phosphated samples had 2-3 times more nodules; none showed evidence of mineralization. All nodules on the phosphated titanium had evidence of mineralization. ELISA analysis revealed no significant differences in IL-1beta production between any of the groups and the EMD groups produced significantly more TGF-beta1 for up to 8 days. Phosphated titanium increased TGF-beta1 and did not adversely affect early osteoblast attachment and function, but accelerated nodule mineralization.

ISBN: 9780542505058Subjects--Topical Terms:

1019378
Health Sciences, Dentistry.

Effects of phosphated titanium and enamel matrix derivatives on osteoblast behavior in vitro.
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100 1 $a Dacy, Justin Anthony. $3 1913265
245 1 0 $a Effects of phosphated titanium and enamel matrix derivatives on osteoblast behavior in vitro.
300 $a 66 p.
500 $a Source: Masters Abstracts International, Volume: 44-04, page: 1804.
500 $a Adviser: Lynne A. Opperman.
502 $a Thesis (M.S.)--The Texas A&M University System Health Science Center, 2006.
520 $a The effects of phosphated titanium and enamel matrix derivatives (EMD) were evaluated on osteoblast attachment and function. Primary rat osteoblasts were cultured on phosphated or non-phosphated titanium for 28 days; half the samples received EMD. Analysis was done using TGF-beta1 and IL-1beta ELISAs, scanning electron microscopy and light microscopy. Microscopic evaluation revealed osteoblasts increasing in number on all discs from day 2 to 28. Nodule formation occurred in all groups and when EMD was added numbers increased. Without EMD and mineralizing media, non-phosphated samples had 2-3 times more nodules; none showed evidence of mineralization. All nodules on the phosphated titanium had evidence of mineralization. ELISA analysis revealed no significant differences in IL-1beta production between any of the groups and the EMD groups produced significantly more TGF-beta1 for up to 8 days. Phosphated titanium increased TGF-beta1 and did not adversely affect early osteoblast attachment and function, but accelerated nodule mineralization.
590 $a School code: 1388.
650 4 $a Health Sciences, Dentistry. $3 1019378
650 4 $a Biology, Cell. $3 1017686
650 4 $a Engineering, Biomedical. $3 1017684
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710 2 0 $a The Texas A&M University System Health Science Center. $3 1250793
773 0 $t Masters Abstracts International $g 44-04.
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791 $a M.S.
792 $a 2006
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1432164