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Temporal lobe epilepsy and sleep: Fo...
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Clemens, Zsofia.
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Temporal lobe epilepsy and sleep: Focus on interictal spikes and memory consolidation (Hungarian text).
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Temporal lobe epilepsy and sleep: Focus on interictal spikes and memory consolidation (Hungarian text)./
作者:
Clemens, Zsofia.
面頁冊數:
71 p.
附註:
Source: Dissertation Abstracts International, Volume: 66-05, Section: B, page: 2436.
Contained By:
Dissertation Abstracts International66-05B.
標題:
Biology, Neuroscience. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3177903
ISBN:
9780542174612
Temporal lobe epilepsy and sleep: Focus on interictal spikes and memory consolidation (Hungarian text).
Clemens, Zsofia.
Temporal lobe epilepsy and sleep: Focus on interictal spikes and memory consolidation (Hungarian text).
- 71 p.
Source: Dissertation Abstracts International, Volume: 66-05, Section: B, page: 2436.
Thesis (Ph.D.)--Semmelweis Egyetem (Hungary), 2005.
Mechanisms underlying sleep, epilepsy and memory are interrelated through several structural and functional factors. Our aim was to investigate some aspects of this interrelationship.
ISBN: 9780542174612Subjects--Topical Terms:
1017680
Biology, Neuroscience.
Temporal lobe epilepsy and sleep: Focus on interictal spikes and memory consolidation (Hungarian text).
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Source: Dissertation Abstracts International, Volume: 66-05, Section: B, page: 2436.
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Consultant: Peter Halasz.
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Thesis (Ph.D.)--Semmelweis Egyetem (Hungary), 2005.
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Mechanisms underlying sleep, epilepsy and memory are interrelated through several structural and functional factors. Our aim was to investigate some aspects of this interrelationship.
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In the first study we examined distribution of temporal lobe epilepsy spikes across different vigilance states recorded via simultaneous intracranial foramen ovate and scalp electrodes. We found that distribution of foramen ovate spikes and scalp spikes is discrepant, the former ones tend to increase during light NREM sleep, while the latter during deep NREM.
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The second study was aimed to investigate the influencing role of different clinical factors on spiking in temporal lobe epilepsy patients. We found that spiking rates during most states and spiking stability across vigilance states increase with epilepsy duration, while relative spiking rates during deep NREM sleep increase with age at epilepsy onset. Moreover, spiking rates during REM were higher in the presence of hippocampal sclerosis, while spiking during waking eyes closed was higher if a patient had secondarily generalised tonic clonic seizures.
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The third study was designed to examine whether different epilepsy syndromes interfere with memory consolidation during sleep. There was no significant difference between right temporal lobe, left temporal lobe and idiopathic generalized epilepsy groups in evening measures, but left temporal patients showed impaired overnight verbal retention and both temporal groups were impaired on overnight visual retention.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3177903
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