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Development of a biomimetic sensor t...

Kindschy, Lisa Marie.

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Development of a biomimetic sensor through molecular imprinting.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Development of a biomimetic sensor through molecular imprinting./
Author:	Kindschy, Lisa Marie.
Description:	96 p.
Notes:	Source: Masters Abstracts International, Volume: 43-06, page: 2300.
Contained By:	Masters Abstracts International43-06.
Subject:	Engineering, Agricultural. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1426434
ISBN:	0542087936

Development of a biomimetic sensor through molecular imprinting.
Kindschy, Lisa Marie.

Development of a biomimetic sensor through molecular imprinting. - 96 p.

Source: Masters Abstracts International, Volume: 43-06, page: 2300.

Thesis (M.S.)--Michigan State University, 2005.

Molecular imprinting is a technique for creating synthetic receptor sites in a polymer. In this research, a molecularly imprinted polymer (MIP) biomimetic sensor was formed for theophylline using a copolymer of two monomers, methacrylic acid and ethylene glycol dimethacrylate. The presence of theophylline in the biomimetic sensor was measured using cyclic voltammetry, specifically, the corresponding peak currents on the voltammograms. The peak currents of the MIP sensor in the presence and absence of theophylline were compared to the blank sensor (non-imprinted polymer).

ISBN: 0542087936Subjects--Topical Terms:

1019504
Engineering, Agricultural.

Development of a biomimetic sensor through molecular imprinting.
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020 $a 0542087936
035 $a (UnM)AAI1426434
035 $a AAI1426434
040 $a UnM $c UnM
100 1 $a Kindschy, Lisa Marie. $3 1907733
245 1 0 $a Development of a biomimetic sensor through molecular imprinting.
300 $a 96 p.
500 $a Source: Masters Abstracts International, Volume: 43-06, page: 2300.
500 $a Adviser: Evangelyn C. Alocilja.
502 $a Thesis (M.S.)--Michigan State University, 2005.
520 $a Molecular imprinting is a technique for creating synthetic receptor sites in a polymer. In this research, a molecularly imprinted polymer (MIP) biomimetic sensor was formed for theophylline using a copolymer of two monomers, methacrylic acid and ethylene glycol dimethacrylate. The presence of theophylline in the biomimetic sensor was measured using cyclic voltammetry, specifically, the corresponding peak currents on the voltammograms. The peak currents of the MIP sensor in the presence and absence of theophylline were compared to the blank sensor (non-imprinted polymer).
520 $a In the initial measurements, the peak current for the MIP sensor on indium tin oxide (ITO) increased by a factor of 5.3 upon addition of theophylline compared to the blank non-imprinted MIP. The ratio of peak currents increased by a factor of 7.5 for the MIP sensor on silicon compared to the blank. The sensitivity of the MIP on ITO was between 2--4 mM theophylline. The concentration of theophylline that resulted in the best signal was 3 mM. The MIP sensor showed no cross reactivity to caffeine, which has a similar chemical structure. This research will provide the foundation for future work in biomimetic sensors by developing durable sensors with longer shelf lives when exposed to rugged and harsh environments.
590 $a School code: 0128.
650 4 $a Engineering, Agricultural. $3 1019504
650 4 $a Chemistry, Polymer. $3 1018428
690 $a 0539
690 $a 0495
710 2 0 $a Michigan State University. $3 676168
773 0 $t Masters Abstracts International $g 43-06.
790 1 0 $a Alocilja, Evangelyn C., $e advisor
790 $a 0128
791 $a M.S.
792 $a 2005
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1426434