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The effects of neonatal exposure to ...

Gates, Allison Michelle.

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The effects of neonatal exposure to environmental estrogen disrupters on ovarian function in female rats.

Record Type:	Electronic resources : Monograph/item
Title/Author:	The effects of neonatal exposure to environmental estrogen disrupters on ovarian function in female rats./
Author:	Gates, Allison Michelle.
Description:	47 p.
Notes:	Source: Masters Abstracts International, Volume: 42-01, page: 0231.
Contained By:	Masters Abstracts International42-01.
Subject:	Health Sciences, Obstetrics and Gynecology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1415162
ISBN:	0496199498

The effects of neonatal exposure to environmental estrogen disrupters on ovarian function in female rats.
Gates, Allison Michelle.

The effects of neonatal exposure to environmental estrogen disrupters on ovarian function in female rats. - 47 p.

Source: Masters Abstracts International, Volume: 42-01, page: 0231.

Thesis (M.S.)--The University of Alabama in Huntsville, 2003.

A single exposure to estrogen disrupting compounds in the neonatal rat impaired later ovarian function. Induced precocious puberty and superovulation were used to assess the effects of such compounds upon ovulation and ovarian and uterine growth. The true estrogens genistein and DES reduced ovarian and uterine weights, but daidzein, a weaker estrogen, did not. No differences were observed with DDT; however, the pesticide dieldrin lowered ova counts. Dioxin, an industrial byproduct, reduced uterine weights, and bisphenol A, a component of plastics, had no significant effects. Control, dioxin- and dieldrin-treated female rats paired overnight with an adult male rat resulted in 100% of control females but only 50% and 20% of dioxin and dieldrin females mating, respectively. These results suggest that genistein, DES, dieldrin, and dioxin can impair reproductive function as a consequence of neonatal exposure. Therefore, environmental exposure to these compounds may have deleterious effects on female fertility.

ISBN: 0496199498Subjects--Topical Terms:

1020690
Health Sciences, Obstetrics and Gynecology.

The effects of neonatal exposure to environmental estrogen disrupters on ovarian function in female rats.
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100 1 $a Gates, Allison Michelle. $3 1900899
245 1 4 $a The effects of neonatal exposure to environmental estrogen disrupters on ovarian function in female rats.
300 $a 47 p.
500 $a Source: Masters Abstracts International, Volume: 42-01, page: 0231.
500 $a Chair: P. Samuel Campbell.
502 $a Thesis (M.S.)--The University of Alabama in Huntsville, 2003.
520 $a A single exposure to estrogen disrupting compounds in the neonatal rat impaired later ovarian function. Induced precocious puberty and superovulation were used to assess the effects of such compounds upon ovulation and ovarian and uterine growth. The true estrogens genistein and DES reduced ovarian and uterine weights, but daidzein, a weaker estrogen, did not. No differences were observed with DDT; however, the pesticide dieldrin lowered ova counts. Dioxin, an industrial byproduct, reduced uterine weights, and bisphenol A, a component of plastics, had no significant effects. Control, dioxin- and dieldrin-treated female rats paired overnight with an adult male rat resulted in 100% of control females but only 50% and 20% of dioxin and dieldrin females mating, respectively. These results suggest that genistein, DES, dieldrin, and dioxin can impair reproductive function as a consequence of neonatal exposure. Therefore, environmental exposure to these compounds may have deleterious effects on female fertility.
590 $a School code: 0278.
650 4 $a Health Sciences, Obstetrics and Gynecology. $3 1020690
650 4 $a Health Sciences, Toxicology. $3 1017752
650 4 $a Biology, Animal Physiology. $3 1017835
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710 2 0 $a The University of Alabama in Huntsville. $3 1017884
773 0 $t Masters Abstracts International $g 42-01.
790 1 0 $a Campbell, P. Samuel, $e advisor
790 $a 0278
791 $a M.S.
792 $a 2003
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1415162