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The effects of a single bout of exer...

Warro, Daniel.

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The effects of a single bout of exercise, with energy replacement, on plasma concentrations of TNF-alpha following consumption of a high-fat, high-carbohydrate mixed meal.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	The effects of a single bout of exercise, with energy replacement, on plasma concentrations of TNF-alpha following consumption of a high-fat, high-carbohydrate mixed meal./
Author:	Warro, Daniel.
Description:	92 p.
Notes:	Source: Masters Abstracts International, Volume: 49-05, page: 3152.
Contained By:	Masters Abstracts International49-05.
Subject:	Health Sciences, Nutrition. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1492450
ISBN:	9781124645094

The effects of a single bout of exercise, with energy replacement, on plasma concentrations of TNF-alpha following consumption of a high-fat, high-carbohydrate mixed meal.
Warro, Daniel.

The effects of a single bout of exercise, with energy replacement, on plasma concentrations of TNF-alpha following consumption of a high-fat, high-carbohydrate mixed meal. - 92 p.

Source: Masters Abstracts International, Volume: 49-05, page: 3152.

Thesis (M.S.)--Colorado State University, 2011.

Background. Cardiovascular disease (CVD) is a major contributor to all-cause mortality in the United States and is a major cause of long-term disability. The risk for CHD typically includes a panel of fasting blood lipids including total, LDL-, and HDL-cholesterol. However, in recent years, the lipemic response to a meal and the accompanying pro-inflammatory molecules are recognized as independent risk factors for the development of CVD. Attention has focused on the vascular endothelium, where an increase in low-grade inflammatory processes leads to the development and progression of vascular insults ultimately contributing to an advanced, complicated atherosclerotic lesion. A large body of evidence suggests that improvements in postprandial lipemia, such as decreased triglycerides (TG) and improved insulin sensitivity can be achieved following an individual exercise session. However, limited data exists elucidating the effects of a prior acute bout of moderate intensity exercise on possible pro-inflammatory changes during the postprandial period. Research consistently shows that an important determinant of the acute metabolic changes associated with a single session of exercise are energy-expenditure dependent. It is of clinical importance to understand the postprandial metabolic response after an acute bout of exercise in which the caloric cost of exercise has been balanced with additional energy intake, i.e. with energy replacement.

ISBN: 9781124645094Subjects--Topical Terms:

1017801
Health Sciences, Nutrition.

The effects of a single bout of exercise, with energy replacement, on plasma concentrations of TNF-alpha following consumption of a high-fat, high-carbohydrate mixed meal.
LDR:04762nam 2200373 4500 001 1405618
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020 $a 9781124645094
035 $a (UMI)AAI1492450
035 $a AAI1492450
040 $a UMI $c UMI
100 1 $a Warro, Daniel. $3 1685019
245 1 4 $a The effects of a single bout of exercise, with energy replacement, on plasma concentrations of TNF-alpha following consumption of a high-fat, high-carbohydrate mixed meal.
300 $a 92 p.
500 $a Source: Masters Abstracts International, Volume: 49-05, page: 3152.
500 $a Advisers: Christopher Melby; Matthew Hickey.
502 $a Thesis (M.S.)--Colorado State University, 2011.
520 $a Background. Cardiovascular disease (CVD) is a major contributor to all-cause mortality in the United States and is a major cause of long-term disability. The risk for CHD typically includes a panel of fasting blood lipids including total, LDL-, and HDL-cholesterol. However, in recent years, the lipemic response to a meal and the accompanying pro-inflammatory molecules are recognized as independent risk factors for the development of CVD. Attention has focused on the vascular endothelium, where an increase in low-grade inflammatory processes leads to the development and progression of vascular insults ultimately contributing to an advanced, complicated atherosclerotic lesion. A large body of evidence suggests that improvements in postprandial lipemia, such as decreased triglycerides (TG) and improved insulin sensitivity can be achieved following an individual exercise session. However, limited data exists elucidating the effects of a prior acute bout of moderate intensity exercise on possible pro-inflammatory changes during the postprandial period. Research consistently shows that an important determinant of the acute metabolic changes associated with a single session of exercise are energy-expenditure dependent. It is of clinical importance to understand the postprandial metabolic response after an acute bout of exercise in which the caloric cost of exercise has been balanced with additional energy intake, i.e. with energy replacement.
520 $a Purpose. Therefore, the purpose of this study was to determine the effects of a single bout of moderate intensity exercise, with energy replacement, on plasma tumor necrosis factor alpha (TNF-alpha) concentrations, measured before and after consumption of a high-fat, high-carbohydrate meal in young, non-obese, sedentary females.
520 $a Methods. Eight, non-obese, sedentary women participated in two seperate high-fat, high-carbohydrate meal tests after undergoing different treatments the following day. For the non-exercise condition (NoEx), the day prior to the postprandial challenge subjects refrained from exercise and consumed a prescribed diet. For the exercise condition (Ex) subjects consumed the same prescribed diet, and completed a cycle ergometer exercise bout at 65% peak heart rate, eliciting a net exercise energy expenditure of &sim;285 kcalories. Subjects then consumed an additional mixed-meal snack to account for the additional energy cost of the exercise. The following morning subjects reported to the laboratory in a fasted state at which time a venous blood sample was obtained. They were then fed a high-fat, high-carbohydrate meal (0.75g fat, 1.1g CHO, and 0.35 g protein/kg body weight), and postprandial venous blood samples were obtained 2, 4, and 6 hours after consumption meal for determination of plasma TNF-alpha concentrations.
520 $a Results. Plasma TNF-alpha concentrations were low in all subjects at baseline and dropped further by the second hour of the postprandial period returning toward baseline in both the Ex and NoEx conditions (time effect, p<0.05). There was not a condition by time interaction on TNF-alpha concentration, nor a main effect of condition.
520 $a Conclusions. The results suggest that a single session of moderate intensity exercise, without an energy deficit, results in no significant effect on fasting or postprandial TNF-alpha plasma concentrations in young, non-obese, sedentary females. However, discretion is advised while interpreting the findings due to the very low concentrations of TNF-alpha measured in the plasma of these young women.
590 $a School code: 0053.
650 4 $a Health Sciences, Nutrition. $3 1017801
650 4 $a Health Sciences, Recreation. $3 1018003
650 4 $a Biology, Physiology. $3 1017816
690 $a 0570
690 $a 0575
690 $a 0719
710 2 $a Colorado State University. $b Food Science & Human Nutrition. $3 1676397
773 0 $t Masters Abstracts International $g 49-05.
790 1 0 $a Melby, Christopher, $e advisor
790 1 0 $a Hickey, Matthew, $e advisor
790 1 0 $a Hickey, Matthew $e committee member
790 1 0 $a Nelson, Tracy $e committee member
790 $a 0053
791 $a M.S.
792 $a 2011
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1492450