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Hormonal and genetic risk factors of...

Razavi, Pedram.

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Hormonal and genetic risk factors of endometrial cancer and trends in incidence and survival of adult acute lymphoblastic leukemia.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Hormonal and genetic risk factors of endometrial cancer and trends in incidence and survival of adult acute lymphoblastic leukemia./
Author:	Razavi, Pedram.
Description:	93 p.
Notes:	Source: Dissertation Abstracts International, Volume: 71-01, Section: B, page: 0199.
Contained By:	Dissertation Abstracts International71-01B.
Subject:	Biology, Genetics. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3389547
ISBN:	9781109562194

Hormonal and genetic risk factors of endometrial cancer and trends in incidence and survival of adult acute lymphoblastic leukemia.
Razavi, Pedram.

Hormonal and genetic risk factors of endometrial cancer and trends in incidence and survival of adult acute lymphoblastic leukemia. - 93 p.

Source: Dissertation Abstracts International, Volume: 71-01, Section: B, page: 0199.

Thesis (Ph.D.)--University of Southern California, 2009.

This dissertation consists of three chapters: The first chapter examines the association between lifetime postmenopausal hormone therapy (HT) use and risk of endometrial cancer using data from a case-control study of invasive endometrial cancer nested within the California Teachers Study (CTS) cohort. In this chapter, I summarize the current literature describing the effect of HT on endometrial cancer. I then present the findings for an analysis of HT and endometrial cancer in the CTS, with new detail on the type of combination therapy. This manuscript has been accepted with minor changes for publication in Cancer Epidemiology, Biomarkers & Prevention.

ISBN: 9781109562194Subjects--Topical Terms:

1017730
Biology, Genetics.

Hormonal and genetic risk factors of endometrial cancer and trends in incidence and survival of adult acute lymphoblastic leukemia.
LDR:02701nam 2200349 4500 001 1403494
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020 $a 9781109562194
035 $a (UMI)AAI3389547
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040 $a UMI $c UMI
100 1 $a Razavi, Pedram. $3 1682757
245 1 0 $a Hormonal and genetic risk factors of endometrial cancer and trends in incidence and survival of adult acute lymphoblastic leukemia.
300 $a 93 p.
500 $a Source: Dissertation Abstracts International, Volume: 71-01, Section: B, page: 0199.
500 $a Adviser: Giske Ursin.
502 $a Thesis (Ph.D.)--University of Southern California, 2009.
520 $a This dissertation consists of three chapters: The first chapter examines the association between lifetime postmenopausal hormone therapy (HT) use and risk of endometrial cancer using data from a case-control study of invasive endometrial cancer nested within the California Teachers Study (CTS) cohort. In this chapter, I summarize the current literature describing the effect of HT on endometrial cancer. I then present the findings for an analysis of HT and endometrial cancer in the CTS, with new detail on the type of combination therapy. This manuscript has been accepted with minor changes for publication in Cancer Epidemiology, Biomarkers & Prevention.
520 $a The second chapter describes the potential impact of genetic and environmental factors on endometrial cancer risk. The analysis focuses on genetic variants in a select number of genes in the sex hormone metabolism pathway and risk of endometrial cancer. I further examine the modifying effect of these variants on the risk of endometrial cancer associated with different HT regimens.
520 $a The third chapter examines patterns of incidence and survival for adult acute lymphoblastic leukemia (ALL) by racial/ethnic groups. Data for these analyses came from the National Cancer Institute, Survival, Epidemiology, and End Results (SEER) database. Previous studies have suggested overall lower survival for some racial/ethnic groups compared to others. We further explore survival patterns by race, ALL subtype and age in the SEER data, which has not been well characterized in the literature.
590 $a School code: 0208.
650 4 $a Biology, Genetics. $3 1017730
650 4 $a Health Sciences, Epidemiology. $3 1019544
650 4 $a Health Sciences, Oncology. $3 1018566
690 $a 0369
690 $a 0766
690 $a 0992
710 2 $a University of Southern California. $b Epidemiology. $3 1682758
773 0 $t Dissertation Abstracts International $g 71-01B.
790 1 0 $a Ursin, Giske, $e advisor
790 1 0 $a Pike, Malcolm C. $e committee member
790 1 0 $a McKean-Cowdin, Roberta $e committee member
790 1 0 $a Spicer, Darcy V. $e committee member
790 $a 0208
791 $a Ph.D.
792 $a 2009
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3389547