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Exploratory Analysis of Pathogen Res...

Bailey, Aubrey.

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Exploratory Analysis of Pathogen Resistance Responsible Genetic Elements in Two Eudicots from Whole Genome Sequence.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Exploratory Analysis of Pathogen Resistance Responsible Genetic Elements in Two Eudicots from Whole Genome Sequence./
Author:	Bailey, Aubrey.
Description:	55 p.
Notes:	Source: Masters Abstracts International, Volume: 49-03, page: 1658.
Contained By:	Masters Abstracts International49-03.
Subject:	Biology, Molecular. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1488199
ISBN:	9781124439105

Exploratory Analysis of Pathogen Resistance Responsible Genetic Elements in Two Eudicots from Whole Genome Sequence.
Bailey, Aubrey.

Exploratory Analysis of Pathogen Resistance Responsible Genetic Elements in Two Eudicots from Whole Genome Sequence. - 55 p.

Source: Masters Abstracts International, Volume: 49-03, page: 1658.

Thesis (M.S.)--Rochester Institute of Technology, 2011.

Agricultural products are becoming more homogenous in order to conform to consumer expectations. In doing so, they have become a high-risk target for widespread crop failure due to pathogens or other agricultural maladies. Presented here are a collection of tools and a work-flow for the wholesale detection and characterization of disease resistance-associated proteins from whole-genome sequences. These techniques were also adapted for identifying potential miRNA regulatory sequences.

ISBN: 9781124439105Subjects--Topical Terms:

1017719
Biology, Molecular.

Exploratory Analysis of Pathogen Resistance Responsible Genetic Elements in Two Eudicots from Whole Genome Sequence.
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020 $a 9781124439105
035 $a (UMI)AAI1488199
035 $a AAI1488199
040 $a UMI $c UMI
100 1 $a Bailey, Aubrey. $3 1682339
245 1 0 $a Exploratory Analysis of Pathogen Resistance Responsible Genetic Elements in Two Eudicots from Whole Genome Sequence.
300 $a 55 p.
500 $a Source: Masters Abstracts International, Volume: 49-03, page: 1658.
500 $a Adviser: Sandra Connelly.
502 $a Thesis (M.S.)--Rochester Institute of Technology, 2011.
520 $a Agricultural products are becoming more homogenous in order to conform to consumer expectations. In doing so, they have become a high-risk target for widespread crop failure due to pathogens or other agricultural maladies. Presented here are a collection of tools and a work-flow for the wholesale detection and characterization of disease resistance-associated proteins from whole-genome sequences. These techniques were also adapted for identifying potential miRNA regulatory sequences.
520 $a Putative R-gene sequences identified from the Malus x Domestica 'Golden Delicious' genome were acquired for verification against wild apple species. Resistance gene analogs were PCR amplified from R-gene associated domains (TIR, NBS, and LRR) in wild apple cultivars. Known R-gene sequences were clustered alongside the PCR analogs and putative R-genes from 'Golden Delicious'.
520 $a A covariance model approach for the de novo detection of 3,187 putative pre-miRNA regulatory sequences is also explored. Vitis vinifera sequences used to build this model were retrieved with 38% efficiency.
520 $a Computational clusters may be useful in the physical mapping of sequences to the chromosomally duplicated gene clusters characteristic of R-genes. Known R-genes included in computational clusters may also clarify the function of the unknown sequences. A possibility exists for the identification of resistance genes that have been lost in the selective breeding of commercial cultivars.
590 $a School code: 0465.
650 4 $a Biology, Molecular. $3 1017719
650 4 $a Agriculture, Plant Pathology. $3 1028950
650 4 $a Biology, Bioinformatics. $3 1018415
690 $a 0307
690 $a 0480
690 $a 0715
710 2 $a Rochester Institute of Technology. $b Bioinformatics. $3 1682340
773 0 $t Masters Abstracts International $g 49-03.
790 1 0 $a Connelly, Sandra, $e advisor
790 1 0 $a Baldo, Angela $e committee member
790 1 0 $a Osier, Michael $e committee member
790 1 0 $a Skuse, Gary $e committee member
790 $a 0465
791 $a M.S.
792 $a 2011
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1488199