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Placebo effect for low back pain: A ...

Lanham, Matthew Aaron.

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Placebo effect for low back pain: A meta-analysis.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Placebo effect for low back pain: A meta-analysis./
Author:	Lanham, Matthew Aaron.
Description:	74 p.
Notes:	Source: Masters Abstracts International, Volume: 48-06, page: 3490.
Contained By:	Masters Abstracts International48-06.
Subject:	Biology, Biostatistics. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1485117
ISBN:	9781124085869

Placebo effect for low back pain: A meta-analysis.
Lanham, Matthew Aaron.

Placebo effect for low back pain: A meta-analysis. - 74 p.

Source: Masters Abstracts International, Volume: 48-06, page: 3490.

Thesis (M.S.)--University of Louisville, 2010.

This study investigates the placebo effect in randomized controlled trials of low back pain. This effect has not been analyzed over time or in respect to low back pain. A meta-analysis was performed using the Pubmed/Medline database for low back pain RCTs with a placebo group. It was shown that in studies using the visual analogue scale (VAS) and the numeric rating scale (NRS-11) that there is a positive placebo effect. While the VAS mean change appears consistent up to 6 months, the limited number of studies available (30, n=1150), did not allow certain time periods to be investigated. For NRS-11 (11, n=477), a general change was calculated based on the first measurement taken. It was established that the expected VAS difference in means was -15.6 (-20.9, -10.2) with a p-value <0.001 and the NRS-11 difference in means to be -1.5 (-2.3, -0.8) with a p-value of < 0.001.

ISBN: 9781124085869Subjects--Topical Terms:

1018416
Biology, Biostatistics.

Placebo effect for low back pain: A meta-analysis.
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245 1 0 $a Placebo effect for low back pain: A meta-analysis.
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500 $a Source: Masters Abstracts International, Volume: 48-06, page: 3490.
502 $a Thesis (M.S.)--University of Louisville, 2010.
520 $a This study investigates the placebo effect in randomized controlled trials of low back pain. This effect has not been analyzed over time or in respect to low back pain. A meta-analysis was performed using the Pubmed/Medline database for low back pain RCTs with a placebo group. It was shown that in studies using the visual analogue scale (VAS) and the numeric rating scale (NRS-11) that there is a positive placebo effect. While the VAS mean change appears consistent up to 6 months, the limited number of studies available (30, n=1150), did not allow certain time periods to be investigated. For NRS-11 (11, n=477), a general change was calculated based on the first measurement taken. It was established that the expected VAS difference in means was -15.6 (-20.9, -10.2) with a p-value <0.001 and the NRS-11 difference in means to be -1.5 (-2.3, -0.8) with a p-value of < 0.001.
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