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New optical tomographic & topographi...

Buytaert, Jan.

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New optical tomographic & topographic techniques for biomedical applications.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	New optical tomographic & topographic techniques for biomedical applications./
Author:	Buytaert, Jan.
Description:	335 p.
Notes:	Source: Dissertation Abstracts International, Volume: 71-07, Section: B, page: 4110.
Contained By:	Dissertation Abstracts International71-07B.
Subject:	Health Sciences, Audiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3416408
ISBN:	9781124104539

New optical tomographic & topographic techniques for biomedical applications.
Buytaert, Jan.

New optical tomographic & topographic techniques for biomedical applications. - 335 p.

Source: Dissertation Abstracts International, Volume: 71-07, Section: B, page: 4110.

Thesis (Ph.D.)--Universiteit Antwerpen (Belgium), 2010.

The mammalian middle ear contains the eardrum and the three auditory ossicles, and forms an impedance match between sound in air and pressure waves in the fluid of the inner ear. Without this intermediate system, with its unsurpassed efficiency and dynamic range, we would be practically deaf. Physics-based modeling of this extremely complex mechanical system is necessary to help our basic understanding of the functioning of hearing. Highly realistic models will make it possible to predict the outcome of surgical interventions and to optimize design of ossicle prostheses and active middle ear implants.

ISBN: 9781124104539Subjects--Topical Terms:

1018138
Health Sciences, Audiology.

New optical tomographic & topographic techniques for biomedical applications.
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020 $a 9781124104539
035 $a (UMI)AAI3416408
035 $a AAI3416408
040 $a UMI $c UMI
100 1 $a Buytaert, Jan. $3 1678225
245 1 0 $a New optical tomographic & topographic techniques for biomedical applications.
300 $a 335 p.
500 $a Source: Dissertation Abstracts International, Volume: 71-07, Section: B, page: 4110.
500 $a Adviser: Joris Dirckx.
502 $a Thesis (Ph.D.)--Universiteit Antwerpen (Belgium), 2010.
520 $a The mammalian middle ear contains the eardrum and the three auditory ossicles, and forms an impedance match between sound in air and pressure waves in the fluid of the inner ear. Without this intermediate system, with its unsurpassed efficiency and dynamic range, we would be practically deaf. Physics-based modeling of this extremely complex mechanical system is necessary to help our basic understanding of the functioning of hearing. Highly realistic models will make it possible to predict the outcome of surgical interventions and to optimize design of ossicle prostheses and active middle ear implants.
520 $a To obtain such models and with realistic output, basic input data is still missing. In this dissertation I developed and used two new optical techniques to obtain two essential sets of data: accurate three-dimensional morphology of the middle ear structures, and elasticity parameters of the eardrum.
520 $a The first technique is a new method for optical tomography of macroscopic biomedical objects, which makes it possible to measure the three-dimensional geometry of the middle ear ossicles and soft tissues which are connecting and suspending them. I made a new and high-resolution version of this orthogonal-plane fluorescence optical sectioning method, to obtain micrometer resolution in macroscopic specimens. The result is thus a complete 3-D model of the middle (and inner) ear of gerbil in unprecedented quality. On top of high-resolution morphological models of the middle ear structures, I applied the technique in other fields of research as well.
520 $a The second device works according to a new optical profilometry technique which allows to measure shape and deformations of the eardrum and other membranes or objects. The approach is called projection moire profilometry, and creates moire interference fringes which contain the height information. I developed a setup which uses liquid crystal panels for grid projection and optical demodulation. Hence no moving parts are present and the setup is entirely digitally controlled. This measurement method is developed to determine the elasticity parameters of the eardrum in-situ. Other surface shapes however can also be measured.
590 $a School code: 1513.
650 4 $a Health Sciences, Audiology. $3 1018138
650 4 $a Engineering, Biomedical. $3 1017684
650 4 $a Physics, Optics. $3 1018756
650 4 $a Biophysics, Medical. $3 1017681
650 4 $a Biophysics, General. $3 1019105
690 $a 0300
690 $a 0541
690 $a 0752
690 $a 0760
690 $a 0786
710 2 $a Universiteit Antwerpen (Belgium). $3 1023974
773 0 $t Dissertation Abstracts International $g 71-07B.
790 1 0 $a Dirckx, Joris, $e advisor
790 $a 1513
791 $a Ph.D.
792 $a 2010
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3416408