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Molecular mechanisms of adult stem c...

Rudolph, K. Lenhard.

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Molecular mechanisms of adult stem cell aging

Record Type:	Electronic resources : Monograph/item
Title/Author:	Molecular mechanisms of adult stem cell aging/ volume editor, Karl Lenhard Rudolph.
other author:	Rudolph, K. Lenhard.
Published:	Basel :S. Karger, : 2010,
Description:	1 online resource :ill. (some col.)
Notes:	A meeting report of the first international Else Kroner-Fresenius-Symposium on Adult Stem Cell Aging
Subject:	Stem cells - Congresses. -
Online resource:	http://content.karger.com/ProdukteDB/produkte.asp?Aktion=showproducts&searchWhat=books&searchParm=toc&ProduktNr=249607
ISBN:	9783805592444

Molecular mechanisms of adult stem cell aging
Molecular mechanisms of adult stem cell aging[electronic resource] /volume editor, Karl Lenhard Rudolph. - Basel :S. Karger,2010 - 1 online resource :ill. (some col.) - Else Kreoner-Fresenius symposia,v.11663-0122 ;. - Else Kreoner-Fresenius symposia ;v.1..

A meeting report of the first international Else Kroner-Fresenius-Symposium on Adult Stem Cell Aging

Includes bibliographical references and index.

There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell-extrinsic alterations affecting the stem cell niche or the macroenvironment. Stem cells have a longer life span than other cell populations and retain a capacity to proliferate and differentiate in adult organs. The aging of adult stem cells plays a key role in the decline of organ maintenance and regenerative potential during aging and during the end stage of chronic diseases. In addition, it can contribute to stem cell transformation and carcinogenesis.Molecular Mechanisms of Adult Stem Cell Aging will appeal to scientists working in the fields such as stem cells, aging, regeneration and cancer. This subject matter should be of interest to physicians and scientists specializing in geriatric medicine, internal medicine, and surgery. It is also likely to be an invaluable resource for medical students and biologists who wish to enhance their understanding of molecular and stem cell biology.

ISBN: 9783805592444Subjects--Topical Terms:

1360842
Stem cells
--Congresses.

LC Class. No.: QH588.S83 / E447 2009

Dewey Class. No.: 616/.02774

National Library of Medicine Call No.: 2010 F-608

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520 $a There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell-extrinsic alterations affecting the stem cell niche or the macroenvironment. Stem cells have a longer life span than other cell populations and retain a capacity to proliferate and differentiate in adult organs. The aging of adult stem cells plays a key role in the decline of organ maintenance and regenerative potential during aging and during the end stage of chronic diseases. In addition, it can contribute to stem cell transformation and carcinogenesis.Molecular Mechanisms of Adult Stem Cell Aging will appeal to scientists working in the fields such as stem cells, aging, regeneration and cancer. This subject matter should be of interest to physicians and scientists specializing in geriatric medicine, internal medicine, and surgery. It is also likely to be an invaluable resource for medical students and biologists who wish to enhance their understanding of molecular and stem cell biology.
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