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Algorithms and methods in structural...

Haspel, Nurit.

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Algorithms and methods in structural bioinformatics

Record Type:	Electronic resources : Monograph/item
Title/Author:	Algorithms and methods in structural bioinformatics/ edited by Nurit Haspel, Filip Jagodzinski, Kevin Molloy.
other author:	Haspel, Nurit.
Published:	Cham :Springer International Publishing : : 2022.,
Description:	ix, 114 p. :ill. (some col.), digital ;24 cm.
[NT 15003449]:	1. Protein-Ligand Binding with Applications in Molecular Docking -- 2. Explaining Small Molecule Binding Specificity with Volumetric Representations of Protein Binding Sites -- 3. Machine Learning-based Approaches for Protein Conformational Exploration -- 4. Low Rank Approximation Methods for identifying Impactful Pairwise Protein Mutations -- 5. Detection and analysis of amino acid insertions and deletions -- 6. DeepTracerWeb Service for Fast and Accurate De Novo Protein Complex Structure Prediction from Cryo-EM.
Contained By:	Springer Nature eBook
Subject:	Structural bioinformatics - Methodology. -
Online resource:	https://doi.org/10.1007/978-3-031-05914-8
ISBN:	9783031059148

Algorithms and methods in structural bioinformatics
Algorithms and methods in structural bioinformatics[electronic resource] /edited by Nurit Haspel, Filip Jagodzinski, Kevin Molloy. - Cham :Springer International Publishing :2022. - ix, 114 p. :ill. (some col.), digital ;24 cm. - Computational biology,2662-2432. - Computational biology..

1. Protein-Ligand Binding with Applications in Molecular Docking -- 2. Explaining Small Molecule Binding Specificity with Volumetric Representations of Protein Binding Sites -- 3. Machine Learning-based Approaches for Protein Conformational Exploration -- 4. Low Rank Approximation Methods for identifying Impactful Pairwise Protein Mutations -- 5. Detection and analysis of amino acid insertions and deletions -- 6. DeepTracerWeb Service for Fast and Accurate De Novo Protein Complex Structure Prediction from Cryo-EM.

The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support this field, a rich set of methods and algorithms are available, addressing a variety of important problems such as protein-protein interactions, the effect of mutations on protein structure and function, and protein structure determination. Despite recent advancements in the field, in particular in protein folding with the development of AlphaFold, many problems still remain unsolved. In this book we focus on a number of topics in Structural Bioinformatics: Cryo-EM structural detection, protein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding.

ISBN: 9783031059148

Standard No.: 10.1007/978-3-031-05914-8doiSubjects--Topical Terms:

3604004
Structural bioinformatics
--Methodology.

LC Class. No.: QH324.2

Dewey Class. No.: 570.285

Algorithms and methods in structural bioinformatics
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245 0 0 $a Algorithms and methods in structural bioinformatics $h [electronic resource] / $c edited by Nurit Haspel, Filip Jagodzinski, Kevin Molloy.
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300 $a ix, 114 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Computational biology, $x 2662-2432
505 0 $a 1. Protein-Ligand Binding with Applications in Molecular Docking -- 2. Explaining Small Molecule Binding Specificity with Volumetric Representations of Protein Binding Sites -- 3. Machine Learning-based Approaches for Protein Conformational Exploration -- 4. Low Rank Approximation Methods for identifying Impactful Pairwise Protein Mutations -- 5. Detection and analysis of amino acid insertions and deletions -- 6. DeepTracerWeb Service for Fast and Accurate De Novo Protein Complex Structure Prediction from Cryo-EM.
520 $a The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support this field, a rich set of methods and algorithms are available, addressing a variety of important problems such as protein-protein interactions, the effect of mutations on protein structure and function, and protein structure determination. Despite recent advancements in the field, in particular in protein folding with the development of AlphaFold, many problems still remain unsolved. In this book we focus on a number of topics in Structural Bioinformatics: Cryo-EM structural detection, protein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding.
650 0 $a Structural bioinformatics $x Methodology. $3 3604004
650 1 4 $a Bioinformatics. $3 553671
650 2 4 $a Health Informatics. $3 892928
700 1 $a Haspel, Nurit. $3 3604001
700 1 $a Jagodzinski, Filip. $3 3604002
700 1 $a Molloy, Kevin. $3 3604003
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830 0 $a Computational biology. $3 3505128
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