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Qin, Yun.

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To assess the predictive value of second trimester, ultrasonic assessment of umbilical coiling index for adverse perinatal outcome.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	To assess the predictive value of second trimester, ultrasonic assessment of umbilical coiling index for adverse perinatal outcome./
Author:	Qin, Yun.
Description:	254 p.
Notes:	Source: Dissertation Abstracts International, Volume: 63-05, Section: B, page: 2320.
Contained By:	Dissertation Abstracts International63-05B.
Subject:	Health Sciences, Obstetrics and Gynecology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3052123
ISBN:	0493680292

To assess the predictive value of second trimester, ultrasonic assessment of umbilical coiling index for adverse perinatal outcome.
Qin, Yun.

To assess the predictive value of second trimester, ultrasonic assessment of umbilical coiling index for adverse perinatal outcome. - 254 p.

Source: Dissertation Abstracts International, Volume: 63-05, Section: B, page: 2320.

Thesis (Ph.D.)--Chinese University of Hong Kong (People's Republic of China), 2002.

<italic>Statistic analysis</italic>. The degrees of agreement between classifications by ultrasound and those recorded at birth were assessed using Cohen's kappa statistic.

ISBN: 0493680292Subjects--Topical Terms:

1020690
Health Sciences, Obstetrics and Gynecology.

To assess the predictive value of second trimester, ultrasonic assessment of umbilical coiling index for adverse perinatal outcome.
LDR:03843nam 2200337 a 45 001 934098
005 20110509
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035 $a (UnM)AAI3052123
035 $a AAI3052123
040 $a UnM $c UnM
100 1 $a Qin, Yun. $3 1257822
245 1 0 $a To assess the predictive value of second trimester, ultrasonic assessment of umbilical coiling index for adverse perinatal outcome.
300 $a 254 p.
500 $a Source: Dissertation Abstracts International, Volume: 63-05, Section: B, page: 2320.
500 $a Supervisor: Michael Scott Rogers.
502 $a Thesis (Ph.D.)--Chinese University of Hong Kong (People's Republic of China), 2002.
520 $a <italic>Statistic analysis</italic>. The degrees of agreement between classifications by ultrasound and those recorded at birth were assessed using Cohen's kappa statistic.
520 $a Multiple linear regression analysis of 8-iso-PGF 2α demonstrated that suspected fetal distress, tight nuchal cord (p < 0.005), and true UCI (p < 0.05) were independent determinants of variation in cord arterial 8-isoprostane concentration.
520 $a <italic>Background</italic>. Absent, decreased, or increased spiraling of the cord is currently thought to increase the risk of cord compression, leading to fetal asphyxia. To date, ultrasonographic investigation of the UCI in the second trimester has not been reported. Knowledge of the development of the umbilical cord, and better sonographic visualization in the second trimester than at term.
520 $a <italic>Objectives</italic>. To determine the ability of ultrasonic UCI in the second trimester and before delivery to predict the true UCI determined at birth and the ability of ultrasonic measurements of UCI to predict the occurrence of: (a) Tight nuchal cord entanglement during delivery; (b) 8-iso-PGF 2α due to umbilical cord compression during labor.
520 $a <italic>Study design and method</italic>. A prospective study of 531 consecutive single uncomplicated normal pregnant women, booking for delivery in the Prince of Wales Hospital, teaching hospital to The Chinese University of Hong Kong, between December 1999 to June 2000. Patients who were undergoing a second trimester ultrasound scan and had their UCI determined. Patients admitted in early labor were asked to assess the UCI again. Women were followed up until delivery to take true UCI. Plasma was collected immediately and determined the sum of free and esterified 8-iso-PGF 2α using the method of Morrow and Roberts, following Folch extraction of plasma lipids.
520 $a <italic>Results</italic>. 531 patients mean (±SD) second trimester UCI was 0.63(±0.01) and before delivery (169 cases) was 0.36(±0.09). Ultrasonic UCI in second trimester was possible in 99% of cases and its decreased linearly with gestational age. The antenatal UCI at second trimester and before delivery was found to predict the postnatal UCI by the equation. We found the degree of agreement between classification based on ultrasound measurements of UCI before delivery and the true measurement of UCI at delivery (kappa = 0.309) was much better than in the second trimester (kappa = 0.02).
520 $a <italic>Conclusion</italic>. We confirmed that second trimester measurement of UCI has a poor predictive ability for hypo-coiling and cord entanglement, operative delivery forfetal distress and fetal asphyxia. The ultrasonic UCI can predict true abnormalities of the cord, as determined at birth.
590 $a School code: 1307.
650 4 $a Health Sciences, Obstetrics and Gynecology. $3 1020690
690 $a 0380
710 2 0 $a Chinese University of Hong Kong (People's Republic of China). $3 1249360
773 0 $t Dissertation Abstracts International $g 63-05B.
790 $a 1307
790 1 0 $a Rogers, Michael Scott, $e advisor
791 $a Ph.D.
792 $a 2002
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3052123