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In vivo measurements of MRI tissue p...

University of California, Berkeley with the University of California, San Francisco.

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In vivo measurements of MRI tissue parameters at various magnetic field strengths.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	In vivo measurements of MRI tissue parameters at various magnetic field strengths./
Author:	Chen, Jyh-Horng.
Description:	204 p.
Notes:	Source: Dissertation Abstracts International, Volume: 53-05, Section: B, page: 2425.
Contained By:	Dissertation Abstracts International53-05B.
Subject:	Engineering, Biomedical. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoeng/servlet/advanced?query=9228596

In vivo measurements of MRI tissue parameters at various magnetic field strengths.
Chen, Jyh-Horng.

In vivo measurements of MRI tissue parameters at various magnetic field strengths. - 204 p.

Source: Dissertation Abstracts International, Volume: 53-05, Section: B, page: 2425.

Thesis (Ph.D.)--University of California, Berkeley with the University of California, San Francisco, 1991.

Magnetic Resonance Imaging (MRI) is extensively used in diagnostic radiology. The main mechanism of its ability to detect lesions is from the difference of relaxation times between normal and diseased tissues. This study's interest is the dependence of relaxation times on magnetic field strength, which in turn changes the contrast of images for the same imaging sequence. By knowing the relaxation times at different fields, one can design an efficient imaging methodology.Subjects--Topical Terms:

1017684
Engineering, Biomedical.

In vivo measurements of MRI tissue parameters at various magnetic field strengths.
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035 $a (UMI)AAI9228596
035 $a AAI9228596
040 $a UMI $c UMI
100 1 $a Chen, Jyh-Horng. $3 1025063
245 1 0 $a In vivo measurements of MRI tissue parameters at various magnetic field strengths.
300 $a 204 p.
500 $a Source: Dissertation Abstracts International, Volume: 53-05, Section: B, page: 2425.
502 $a Thesis (Ph.D.)--University of California, Berkeley with the University of California, San Francisco, 1991.
520 $a Magnetic Resonance Imaging (MRI) is extensively used in diagnostic radiology. The main mechanism of its ability to detect lesions is from the difference of relaxation times between normal and diseased tissues. This study's interest is the dependence of relaxation times on magnetic field strength, which in turn changes the contrast of images for the same imaging sequence. By knowing the relaxation times at different fields, one can design an efficient imaging methodology.
520 $a In this dissertation, we measure in vivo relaxation times of rat tissues and one tumor model between 0.064 Tesla and 4.85 Tesla, which covers most of the magnetic fields available for MRI. Error analysis of the derived parameters are performed. Proper imaging parameters are chosen to produce minimum error relaxation time. It is shown that T$\sb1$ increases with field while T$\sb2$ decreases with increasing field strength. The relationship between relaxation times and water content of tumor and its host tissue is also studied and compared with the fast exchange two site model. Image contrast and signal difference based on the data at different fields are then presented.
520 $a Two other tissue parameters, the diffusion coefficient and perfusion ratio, of rat brain are also measured at 4.85 Tesla. We show that optimal sequences with flow compensation and gradient-sensitization give good results in both parameter measurements. With higher signal-to-noise ratio and more accurate gradient setting, the error in both measurements can be further reduced.
590 $a School code: 1066.
650 4 $a Engineering, Biomedical. $3 1017684
650 4 $a Health Sciences, Radiology. $3 1019076
690 $a 0541
690 $a 0574
710 2 $a University of California, Berkeley with the University of California, San Francisco. $3 1025062
773 0 $t Dissertation Abstracts International $g 53-05B.
790 $a 1066
791 $a Ph.D.
792 $a 1991
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoeng/servlet/advanced?query=9228596