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Sequesteration of Lead, Cadmium and ...

Monachese, Marc Alberto,

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Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential // Marc Alberto Monachese.
作者:	Monachese, Marc Alberto,
面頁冊數:	1 electronic resource (155 pages)
附註:	Source: Masters Abstracts International, Volume: 84-02.
Contained By:	Masters Abstracts International84-02.
標題:	Lead content. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29239946
ISBN:	9798841584988

Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential /
Monachese, Marc Alberto,

Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential /Marc Alberto Monachese. - 1 electronic resource (155 pages)

Source: Masters Abstracts International, Volume: 84-02.

Toxic metals are a class of elements with no biological role but with extreme toxicity. On average only 50% of ingested toxins are absorbed into the human body, for reasons still unknown. It was hypothesized that the gut microbiota plays a role in reducing toxin absorbance. The aim of this study was to determine if constituents of the gut, namely Lactobacillus species, are able to sequester arsenic, lead and cadmium from the environment. Lactobacilli were incubated with the metals, both in vitro and with a Caco-2 cell line. Analysis of metal concentrations was conducted to determine if these were reduced by lactobacilli and if this in turn lowered mortality of the Caco-2 cells, and to establish if lactobacilli could block transport of metals across a cell layer. In vitro studies and electron microscopy showed that lactobacilli had significant binding potential to the metals lead and cadmium. In addition, they conferred protection of Caco-2 cells from toxicity with less metal binding to the epithelial cell surfaces. This supports my hypothesis and raises the concept of using probiotic lactobacilli, perhaps in a food formulation, to reduce heavy metal exposure and poisoning. A yogurt formulation was created using two strains with metal-binding potential, and this could be tested in the future.

English

ISBN: 9798841584988Subjects--Topical Terms:

3687496
Lead content.

Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential /
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