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An Integrative Organismal Approach T...

Peralta Martinez, Karen Y.,

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An Integrative Organismal Approach Testing the Effects of Complex Dietary Fibers on Mammalian Gut Physiology and Microbiome /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	An Integrative Organismal Approach Testing the Effects of Complex Dietary Fibers on Mammalian Gut Physiology and Microbiome // Karen Y Peralta Martinez.
作者:	Peralta Martinez, Karen Y.,
面頁冊數:	1 electronic resource (224 pages)
附註:	Source: Dissertations Abstracts International, Volume: 86-11, Section: B.
Contained By:	Dissertations Abstracts International86-11B.
標題:	Biology. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31936682
ISBN:	9798314867549

An Integrative Organismal Approach Testing the Effects of Complex Dietary Fibers on Mammalian Gut Physiology and Microbiome /
Peralta Martinez, Karen Y.,

An Integrative Organismal Approach Testing the Effects of Complex Dietary Fibers on Mammalian Gut Physiology and Microbiome /Karen Y Peralta Martinez. - 1 electronic resource (224 pages)

Source: Dissertations Abstracts International, Volume: 86-11, Section: B.

The fields of comparative physiology and microbial ecology have increasingly acknowledged the vital role of the gut microbiome in animal function. Feeding strategies- herbivory, carnivory, and omnivory-significantly influence how animals obtain and utilize energy for survival, reproduction, and physiological performance. While comparative physiology has long explored structural adaptations and plastic responses to environmental variables like food quantity and quality, the contribution of gut microbes to these adaptations remains underexplored. This dissertation addresses key gaps by integrating microbial and physiological perspectives across dietary strategies in wild mammals. Chapter 2 evaluates the effectiveness of different preservation solutions for microbial culturing of cecal content samples from Marmota monax (groundhogs). Results suggest that solutions containing multiple cryoprotectants better maintain bacterial viability and community diversity during storage and transport. Chapters 3 and 4 adopt an integrative systems approach to examine how diet quality (low-quality, plant-based fiber diets vs. high-quality, protein-rich diets) affects the gut microbiome and physiological plasticity in small rodents representing different feeding strategies. Chapter 3 reveals distinct physiological responses at multiple biological levels-tissue, cellular, protein, and gene expression-especially under low-quality diets. Notably, herbivores and carnivores exhibited gut microbiota with greater functional adaptability than omnivores in response to dietary shifts. In Chapter 4, rodents fed low-quality diets showed complete digestion of fibrous material, albeit with reduced overall digestive efficiency. Additionally, cecal microbiome analysis indicated a decrease in bacterial richness and diversity in mice consuming fiber-heavy diets. Together, these findings underscore the central role of gut microbes in facilitating dietary adaptation and physiological flexibility across feeding strategies in wild mammals. They also emphasize the need for improved microbial preservation techniques for field-collected samples. Future research should broaden species representation, incorporate longitudinal designs to track microbiome dynamics over time, and examine how environmental stressors, such as climate change, modulate the diet-microbiome-host axis. Further refinement of microbial storage methods will also enhance our ability to study functional microbial ecology in natural systems.

English

ISBN: 9798314867549Subjects--Topical Terms:

522710
Biology.
Subjects--Index Terms:

Cecum

An Integrative Organismal Approach Testing the Effects of Complex Dietary Fibers on Mammalian Gut Physiology and Microbiome /
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520 $a The fields of comparative physiology and microbial ecology have increasingly acknowledged the vital role of the gut microbiome in animal function. Feeding strategies- herbivory, carnivory, and omnivory-significantly influence how animals obtain and utilize energy for survival, reproduction, and physiological performance. While comparative physiology has long explored structural adaptations and plastic responses to environmental variables like food quantity and quality, the contribution of gut microbes to these adaptations remains underexplored. This dissertation addresses key gaps by integrating microbial and physiological perspectives across dietary strategies in wild mammals. Chapter 2 evaluates the effectiveness of different preservation solutions for microbial culturing of cecal content samples from Marmota monax (groundhogs). Results suggest that solutions containing multiple cryoprotectants better maintain bacterial viability and community diversity during storage and transport. Chapters 3 and 4 adopt an integrative systems approach to examine how diet quality (low-quality, plant-based fiber diets vs. high-quality, protein-rich diets) affects the gut microbiome and physiological plasticity in small rodents representing different feeding strategies. Chapter 3 reveals distinct physiological responses at multiple biological levels-tissue, cellular, protein, and gene expression-especially under low-quality diets. Notably, herbivores and carnivores exhibited gut microbiota with greater functional adaptability than omnivores in response to dietary shifts. In Chapter 4, rodents fed low-quality diets showed complete digestion of fibrous material, albeit with reduced overall digestive efficiency. Additionally, cecal microbiome analysis indicated a decrease in bacterial richness and diversity in mice consuming fiber-heavy diets. Together, these findings underscore the central role of gut microbes in facilitating dietary adaptation and physiological flexibility across feeding strategies in wild mammals. They also emphasize the need for improved microbial preservation techniques for field-collected samples. Future research should broaden species representation, incorporate longitudinal designs to track microbiome dynamics over time, and examine how environmental stressors, such as climate change, modulate the diet-microbiome-host axis. Further refinement of microbial storage methods will also enhance our ability to study functional microbial ecology in natural systems.
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