東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁 到查詢結果 [ null ]

切換: 標籤 | MARC模式 | ISBD

Applications of Hybrid Metaheuristic...

McCumber, Joshua A.,

FindBook

Google Book

Amazon

博客來

Applications of Hybrid Metaheuristic Algorithms for Optimization of Production Operations and Transportation Management in Medical Radioisotope Production /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Applications of Hybrid Metaheuristic Algorithms for Optimization of Production Operations and Transportation Management in Medical Radioisotope Production // Joshua A McCumber.
作者:	McCumber, Joshua A.,
面頁冊數:	1 electronic resource (184 pages)
附註:	Source: Dissertations Abstracts International, Volume: 86-06, Section: B.
Contained By:	Dissertations Abstracts International86-06B.
標題:	Engineering. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31762391
ISBN:	9798346849643

Applications of Hybrid Metaheuristic Algorithms for Optimization of Production Operations and Transportation Management in Medical Radioisotope Production /
McCumber, Joshua A.,

Applications of Hybrid Metaheuristic Algorithms for Optimization of Production Operations and Transportation Management in Medical Radioisotope Production /Joshua A McCumber. - 1 electronic resource (184 pages)

Source: Dissertations Abstracts International, Volume: 86-06, Section: B.

Particle accelerators utilized in producing medical radioisotopes are often at a competitive disadvantage to nuclear reactors for producing the neutron-abundant species currently dominating the diagnostic and therapeutic medical use landscape. Reliance on foreign supply chains for isotopes such as 99mTc has seen shortages in the previous decades, affecting the access to care for many Americans. Often confronted with competitive disadvantages, businesses have hesitated to enter this business space and are dilatory in meeting domestic production needs. The legislative drive to eliminate uranium-based targets for irradiation and production of medical radioisotopes in overseas reactors presents additional complications to the supply chain. Alternate production pathway facilities manufacturing neutron and proton-abundant isotope species may be necessary to realize these goals. Production and logistics optimization provide complex problem spaces to be examined to increase the competitiveness of particle accelerator-based production strategies. The application of metaheuristic algorithms to aid in the planning and executing the production and transportation of decaying inventories shows effective increases in cost and time savings compared to conventional planning methodologies. Regional accelerator-based production centers may bridge the gap and decrease reliance on foreign radioisotope supply chains, increasing domestic access to radiotherapy, diagnosis, and palliative care.

English

ISBN: 9798346849643Subjects--Topical Terms:

586835
Engineering.
Subjects--Index Terms:

Particle accelerators

Applications of Hybrid Metaheuristic Algorithms for Optimization of Production Operations and Transportation Management in Medical Radioisotope Production /
LDR:03151nmm a22004693i 4500 001 2429823
005 20250430094139.5
006 m o d
007 cr|nu||||||||
008 261011s2025 miu||||||m |||||||eng d
020 $a 9798346849643
035 $a (MiAaPQD)AAI31762391
035 $a AAI31762391
040 $a MiAaPQD $b eng $c MiAaPQD $e rda
100 1 $a McCumber, Joshua A., $e author. $3 3817866
245 1 0 $a Applications of Hybrid Metaheuristic Algorithms for Optimization of Production Operations and Transportation Management in Medical Radioisotope Production / $c Joshua A McCumber.
264 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2025
300 $a 1 electronic resource (184 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Dissertations Abstracts International, Volume: 86-06, Section: B.
500 $a Advisors: Bierce, Jonathan; Blackford, Joseph P. Committee members: Biemer, Steven.
502 $b D.Engr. $c The George Washington University $d 2025.
520 $a Particle accelerators utilized in producing medical radioisotopes are often at a competitive disadvantage to nuclear reactors for producing the neutron-abundant species currently dominating the diagnostic and therapeutic medical use landscape. Reliance on foreign supply chains for isotopes such as 99mTc has seen shortages in the previous decades, affecting the access to care for many Americans. Often confronted with competitive disadvantages, businesses have hesitated to enter this business space and are dilatory in meeting domestic production needs. The legislative drive to eliminate uranium-based targets for irradiation and production of medical radioisotopes in overseas reactors presents additional complications to the supply chain. Alternate production pathway facilities manufacturing neutron and proton-abundant isotope species may be necessary to realize these goals. Production and logistics optimization provide complex problem spaces to be examined to increase the competitiveness of particle accelerator-based production strategies. The application of metaheuristic algorithms to aid in the planning and executing the production and transportation of decaying inventories shows effective increases in cost and time savings compared to conventional planning methodologies. Regional accelerator-based production centers may bridge the gap and decrease reliance on foreign radioisotope supply chains, increasing domestic access to radiotherapy, diagnosis, and palliative care.
546 $a English
590 $a School code: 0075
650 4 $a Engineering. $3 586835
650 4 $a Mathematics. $3 515831
650 4 $a Nuclear physics. $3 517741
650 4 $a Medicine. $3 641104
650 4 $a Health sciences. $3 3168359
653 $a Particle accelerators
653 $a Nuclear reactors
653 $a Metaheuristic algorithms
653 $a Foreign radioisotope supply chains
653 $a Radiotherapy
690 $a 0537
690 $a 0756
690 $a 0405
690 $a 0566
690 $a 0564
710 2 $a The George Washington University. $b Engineering Management. $e degree granting institution. $3 3770547
720 1 $a Bierce, Jonathan $e degree supervisor.
720 1 $a Blackford, Joseph P. $e degree supervisor.
773 0 $t Dissertations Abstracts International $g 86-06B.
790 $a 0075
791 $a D.Engr.
792 $a 2025
856 4 0 $u https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31762391