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Sex Differences in Pain Perception a...

Traylor, Zachary.

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Sex Differences in Pain Perception and Event Related Neural Correlates of Pain.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Sex Differences in Pain Perception and Event Related Neural Correlates of Pain./
Author:	Traylor, Zachary.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2023,
Description:	48 p.
Notes:	Source: Masters Abstracts International, Volume: 84-11.
Contained By:	Masters Abstracts International84-11.
Subject:	Physiology. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30400552
ISBN:	9798379472139

Sex Differences in Pain Perception and Event Related Neural Correlates of Pain.
Traylor, Zachary.

Sex Differences in Pain Perception and Event Related Neural Correlates of Pain. - Ann Arbor : ProQuest Dissertations & Theses, 2023 - 48 p.

Source: Masters Abstracts International, Volume: 84-11.

Thesis (M.Sc.)--North Carolina State University, 2023.

Women have a higher incidence of pain-related conditions, reports of pain, and are generally considered by medical professionals to have less tolerance for pain. These beliefs have pervaded society as well, with many believing women to be weaker, or sometimes stronger, than men. The effect on clinical research has also been profound, with many clinical trials and models failing to account for differences between the sexes in dangerous ways. Actual consensus in research on the subject of this difference has become a debate, with most researchers supporting the difference, some denying it, some explaining that it's complicated, and others still failing to report on it in their results.This study seeks to provide a neuroscientific approach to this problem via analyzing eventrelated EEG components indicative of pain, paired with a traditional behavioral analysis of pain perception. Previous research has largely neglected the ability of neuroscience to shed further light on differences in pain processing between men and women. By leveraging the well-studied painevoked potential, we demonstrate that the difference between men and women regarding pain perception may not be as reliable as literature suggests.A public dataset of 51 subjects was used (25 female) containing physiological and behavioral data, and a repeated-measures ANCOVA was conducted to determine the impact of sex (male or female) on pain thresholds, verbal pain ratings, N1 amplitude, N2 amplitude, P2 amplitude, and Gamma band power while controlling for between-subject differences and stimulus intensity. Results indicate no significant differences between men and women in any of the measured dependent variables. We propose potential alternative sources for the well-studied paingap between sexes, including psych-sociocultural sources and the need for more nuanced models, as our results do not support the existence of this pain gap between men and women in response to laser-evoked pain. In total, this study presents a novel application of statistics and event-related EEG analysis to question the extent of the difference between men and women's pain perception.

ISBN: 9798379472139Subjects--Topical Terms:

518431
Physiology.

Sex Differences in Pain Perception and Event Related Neural Correlates of Pain.
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