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Acute and Chronic Dialysis During the Coronavirus Disease 2019 (COVID-19) Pandemic.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Acute and Chronic Dialysis During the Coronavirus Disease 2019 (COVID-19) Pandemic./
作者:
Hsu, Caroline M.
出版者:
Ann Arbor : ProQuest Dissertations & Theses, : 2022,
面頁冊數:
97 p.
附註:
Source: Masters Abstracts International, Volume: 83-12.
Contained By:
Masters Abstracts International83-12.
標題:
Health sciences. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29062099
ISBN:
9798819333365
Acute and Chronic Dialysis During the Coronavirus Disease 2019 (COVID-19) Pandemic.
Hsu, Caroline M.
Acute and Chronic Dialysis During the Coronavirus Disease 2019 (COVID-19) Pandemic.
- Ann Arbor : ProQuest Dissertations & Theses, 2022 - 97 p.
Source: Masters Abstracts International, Volume: 83-12.
Thesis (M.S.)--Tufts University-Graduate School of Biomedical Sciences, 2022.
This item must not be sold to any third party vendors.
Throughout the coronavirus disease 2019 (COVID-19) pandemic, patients receiving dialysis have been particularly vulnerable to poor outcomes, and in the work presented here, we have sought to characterize their epidemiology at each phase. Among critically ill patients with COVID-19 who initiated dialysis for acute kidney injury, greater baseline kidney function and greater urine output at the time of dialysis initiation were associated with kidney recovery. During this early phase of the pandemic (spring and early summer of 2020), patients receiving chronic dialysis were found to be at high risk of developing COVID-19, and among those with COVID-19, 90-day mortality approached 25%. As the pandemic evolved, testing became more widely available, thus increasing diagnosis of mild and asymptomatic cases, and infection control measures were widely implemented in healthcare facilities. During this phase of the pandemic (fall and early winter of 2020), in-center dialysis did not have greater association with COVID-19 than home dialysis, once residence in a long-term care facility was adjusted for. Lastly, vaccines against severe acute respiratory syndrome coronavirus 2 became available in December 2021. Patients receiving chronic dialysis were found to have a robust initial seroresponse; however, this was observed to wane over time, suggesting that additional vaccine doses may be appropriate for this vulnerable population. .
ISBN: 9798819333365Subjects--Topical Terms:
3168359
Health sciences.
Subjects--Index Terms:
Coronavirus disease 2019
Acute and Chronic Dialysis During the Coronavirus Disease 2019 (COVID-19) Pandemic.
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Throughout the coronavirus disease 2019 (COVID-19) pandemic, patients receiving dialysis have been particularly vulnerable to poor outcomes, and in the work presented here, we have sought to characterize their epidemiology at each phase. Among critically ill patients with COVID-19 who initiated dialysis for acute kidney injury, greater baseline kidney function and greater urine output at the time of dialysis initiation were associated with kidney recovery. During this early phase of the pandemic (spring and early summer of 2020), patients receiving chronic dialysis were found to be at high risk of developing COVID-19, and among those with COVID-19, 90-day mortality approached 25%. As the pandemic evolved, testing became more widely available, thus increasing diagnosis of mild and asymptomatic cases, and infection control measures were widely implemented in healthcare facilities. During this phase of the pandemic (fall and early winter of 2020), in-center dialysis did not have greater association with COVID-19 than home dialysis, once residence in a long-term care facility was adjusted for. Lastly, vaccines against severe acute respiratory syndrome coronavirus 2 became available in December 2021. Patients receiving chronic dialysis were found to have a robust initial seroresponse; however, this was observed to wane over time, suggesting that additional vaccine doses may be appropriate for this vulnerable population. .
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