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Assessing the Quorum Sensing Circuit in Vibrio coralliilyticus and Its Implications in Coral Pathogenesis.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Assessing the Quorum Sensing Circuit in Vibrio coralliilyticus and Its Implications in Coral Pathogenesis./
Author:	Klempic, Emra.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2022,
Description:	36 p.
Notes:	Source: Masters Abstracts International, Volume: 83-12.
Contained By:	Masters Abstracts International83-12.
Subject:	Biology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29215450
ISBN:	9798834015116

Assessing the Quorum Sensing Circuit in Vibrio coralliilyticus and Its Implications in Coral Pathogenesis.
Klempic, Emra.

Assessing the Quorum Sensing Circuit in Vibrio coralliilyticus and Its Implications in Coral Pathogenesis. - Ann Arbor : ProQuest Dissertations & Theses, 2022 - 36 p.

Source: Masters Abstracts International, Volume: 83-12.

Thesis (M.S.)--Indiana University, 2022.

This item must not be sold to any third party vendors.

Quorum sensing (QS) is an intracellular communication process that bacteria use to transition from individual behaviors to group behaviors. QS coordinates gene expression on a population wide-scale, and it is widely dispersed in Gram-positive and Gram-negative bacterial clades. This process is dependent on the production, release, and detection of signaling molecules known as autoinducers (AIs). AIs follow a distinct pattern of biosynthesis, and the concentration is dependent on bacterial growth phase. At low cell density (LCD), the local concentration of AIs is low, subsequently leading to the expression of genes responsible for individual behaviors. As cell density increases to high cell density (HCD), the local extracellular concentration of AIs increases proportionally with cell number, leading to the expression of genes responsible for group behaviors and repression of individual behavior genes. QS plays an important role in the synthesis of virulence factors, antibiotics, biofilms, motility, bioluminescence, competence, and sporulation in numerous bacteria. Understanding QS is crucial to combatting antibiotic resistance, as disruption in these intracellular communication pathways typically repress genes that encode virulence in ecological-, economical-, and health-relevant pathogens. Vibrio coralliilyticus is a Gram-negative marine bacterium with a broad host range and an etiological agent of coral disease. Its pathogenicity in coral has been well-documented but the role of QS in virulence is currently under investigation. In this literature review, I will introduce background information on QS systems in V. coralliilyticus, and commonalities with its close relative Vibrio campbellii, as well as its implications in coral pathogenesis.

ISBN: 9798834015116Subjects--Topical Terms:

522710
Biology.
Subjects--Index Terms:

Coral reefs

Assessing the Quorum Sensing Circuit in Vibrio coralliilyticus and Its Implications in Coral Pathogenesis.
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