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Clinical Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-Surgical Treatment of Peri-Implant Disease.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Clinical Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-Surgical Treatment of Peri-Implant Disease./
作者:	Garcia, Marcos.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2021,
面頁冊數:	84 p.
附註:	Source: Masters Abstracts International, Volume: 83-02.
Contained By:	Masters Abstracts International83-02.
標題:	Dentistry. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28644277
ISBN:	9798522945121

Clinical Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-Surgical Treatment of Peri-Implant Disease.
Garcia, Marcos.

Clinical Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-Surgical Treatment of Peri-Implant Disease. - Ann Arbor : ProQuest Dissertations & Theses, 2021 - 84 p.

Source: Masters Abstracts International, Volume: 83-02.

Thesis (M.Sc.D.)--The University of Texas School of Dentistry at Houston, 2021.

This item must not be sold to any third party vendors.

Background: Laser antimicrobial photodynamic therapy has been advocated as an adjunct to traditional mechanical debridement of implants suffering from peri-implant inflammation. This study aims to compare clinical outcomes specifically changes in bleeding on probing (BOP) and pocket depth (PD) after mechanical debridement of implant surfaces at sites exhibiting plaque induced inflammation with or without adjunctive laser antimicrobial photodynamic therapy (aPDT).Methods: This a randomized double blinded clinical control study designed to assess improved clinical outcomes with the use of aPDT as an adjunct to mechanical debridement in the treatment of peri-implant diseases. Thirty-four (34) patients were recruited. Clinical measurements including bleeding on probing (BOP), pocket depth (PD), and plaque were measured at baseline, 6 weeks, and 12 weeks after therapy. The 2017 Periodontology World Workshop classification was used to diagnose implants as peri-implant mucositis or peri-implantitis. Only diseased implants were included and only one implant per patient was studied. Our hypothesis is that implant sites diagnosed with either peri-implant mucositis or peri-implantitis treated with mechanical debridement and adjunctive aPDT will have greater reduction in BOP and PD than those sites treated with mechanical debridement alone.Results: For the peri-implantitis group there was no statistically significant difference in clinical parameters between test and control groups (P ≤ 0.05) between time points. For the peri-implant mucositis group, there was no statistically significant difference in clinical parameters between test and control groups (p ≤ 0.05) between time points. Correlation noted between an increasing plaque count and increased BOP (p = 0.0022), PD mean (p = 0.0184), and deepest PD (p = 0.05). In the peri-implantitis group, generalized linear mixed model statistical analysis showed that comparing between baseline and 6 weeks and 12-week time points, there was an overall statistically significant reduction in BOP (p < 0.02), PD mean (p < 0.0005), and deepest PD (p < 0.007). For the peri-implant mucositis group, analysis showed that comparing between baseline and 6 weeks and 12-week time points, there was an overall statistically significant reduction in BOP (p < 0.001), PD mean (p < 0.0005), deepest PD (p < 0.007), and plaque count (p < 0.014).Conclusion: Non-surgical treatment of both peri-implant mucositis and peri-implantitis is effective in decreasing peri-implant inflammation and improving clinical parameters of BOP, PD, and plaque. There was no statistically significant difference in clinical outcomes between those implants treated with adjunctive aPDT and those treated without adjunctive aPDT.

ISBN: 9798522945121Subjects--Topical Terms:

828971
Dentistry.
Subjects--Index Terms:

Implant

Clinical Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-Surgical Treatment of Peri-Implant Disease.
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500 $a Source: Masters Abstracts International, Volume: 83-02.
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506 $a This item must not be sold to any third party vendors.
520 $a Background: Laser antimicrobial photodynamic therapy has been advocated as an adjunct to traditional mechanical debridement of implants suffering from peri-implant inflammation. This study aims to compare clinical outcomes specifically changes in bleeding on probing (BOP) and pocket depth (PD) after mechanical debridement of implant surfaces at sites exhibiting plaque induced inflammation with or without adjunctive laser antimicrobial photodynamic therapy (aPDT).Methods: This a randomized double blinded clinical control study designed to assess improved clinical outcomes with the use of aPDT as an adjunct to mechanical debridement in the treatment of peri-implant diseases. Thirty-four (34) patients were recruited. Clinical measurements including bleeding on probing (BOP), pocket depth (PD), and plaque were measured at baseline, 6 weeks, and 12 weeks after therapy. The 2017 Periodontology World Workshop classification was used to diagnose implants as peri-implant mucositis or peri-implantitis. Only diseased implants were included and only one implant per patient was studied. Our hypothesis is that implant sites diagnosed with either peri-implant mucositis or peri-implantitis treated with mechanical debridement and adjunctive aPDT will have greater reduction in BOP and PD than those sites treated with mechanical debridement alone.Results: For the peri-implantitis group there was no statistically significant difference in clinical parameters between test and control groups (P ≤ 0.05) between time points. For the peri-implant mucositis group, there was no statistically significant difference in clinical parameters between test and control groups (p ≤ 0.05) between time points. Correlation noted between an increasing plaque count and increased BOP (p = 0.0022), PD mean (p = 0.0184), and deepest PD (p = 0.05). In the peri-implantitis group, generalized linear mixed model statistical analysis showed that comparing between baseline and 6 weeks and 12-week time points, there was an overall statistically significant reduction in BOP (p < 0.02), PD mean (p < 0.0005), and deepest PD (p < 0.007). For the peri-implant mucositis group, analysis showed that comparing between baseline and 6 weeks and 12-week time points, there was an overall statistically significant reduction in BOP (p < 0.001), PD mean (p < 0.0005), deepest PD (p < 0.007), and plaque count (p < 0.014).Conclusion: Non-surgical treatment of both peri-implant mucositis and peri-implantitis is effective in decreasing peri-implant inflammation and improving clinical parameters of BOP, PD, and plaque. There was no statistically significant difference in clinical outcomes between those implants treated with adjunctive aPDT and those treated without adjunctive aPDT.
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650 4 $a Cytokines. $3 687114
650 4 $a Bacteria. $3 550366
650 4 $a Biological products. $3 656054
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