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Genetic influences on the neural cor...

Handwerger, Kathryn L.

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Genetic influences on the neural correlates of emotional memory.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Genetic influences on the neural correlates of emotional memory./
作者:	Handwerger, Kathryn L.
面頁冊數:	57 p.
附註:	Source: Masters Abstracts International, Volume: 47-01, page: 6070.
Contained By:	Masters Abstracts International47-01.
標題:	Experimental psychology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1456602
ISBN:	9780549709008

Genetic influences on the neural correlates of emotional memory.
Handwerger, Kathryn L.

Genetic influences on the neural correlates of emotional memory. - 57 p.

Source: Masters Abstracts International, Volume: 47-01, page: 6070.

Thesis (M.S.)--Tufts University, 2008.

Previous research has demonstrated that arousing emotional stimuli are remembered better than neutral stimuli, and that this effect is likely driven by the amygdala and hippocampus. However, whether the emotional modulation of memory is affected by specific genes previously identified as affecting limbic function (e.g., polymorphisms of the serotonin transporter and BDNF genes) is unknown. The current study used fMRI in healthy individuals (n=19; 10 male) to assess BOLD signal during the viewing of positive, negative, and neutral pictures from the International Affective Picture System. A surprise memory test was administered offline one week later. Behavioral results revealed a significant effect of picture type (p<.01), indicating better memory for emotional (positive and negative) than neutral pictures, even when controlling for false alarm rates (d'). Furthermore, participants remembered significantly more negative than positive pictures. fMRI analyses revealed significantly greater activation in the amygdala and hippocampus during the viewing of subsequently remembered emotional versus neutral pictures. Similarly, greater bilateral hippocampal activity occurred when comparing neutral pictures that were subsequently remembered to those that were forgotten. Genetic data are currently being analyzed. These preliminary results support the idea that emotional information is better remembered than neutral information, and that activation of the amygdala and hippocampus during encoding helps to account for this difference. Additional analyses are expected to illuminate the role of genetics in the modulation of emotional memory.

ISBN: 9780549709008

LCCN: AAI1456602Subjects--Topical Terms:

2144733
Experimental psychology.

Genetic influences on the neural correlates of emotional memory.
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