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Photodegradation of selected endocri...

Young, Robert B.

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Photodegradation of selected endocrine and pharmaceutically active compounds under environmentally relevant conditions -- Processes and products.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Photodegradation of selected endocrine and pharmaceutically active compounds under environmentally relevant conditions -- Processes and products./
Author:	Young, Robert B.
Description:	244 p.
Notes:	Source: Dissertation Abstracts International, Volume: 75-10(E), Section: B.
Contained By:	Dissertation Abstracts International75-10B(E).
Subject:	Environmental science. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3624417
ISBN:	9781303977510

Photodegradation of selected endocrine and pharmaceutically active compounds under environmentally relevant conditions -- Processes and products.
Young, Robert B.

Photodegradation of selected endocrine and pharmaceutically active compounds under environmentally relevant conditions -- Processes and products. - 244 p.

Source: Dissertation Abstracts International, Volume: 75-10(E), Section: B.

Thesis (Ph.D.)--Colorado State University, 2014.

This item must not be sold to any third party vendors.

Within the past few decades, books such as Silent Spring and Our Stolen Future have done much to raise the public's awareness of the threat to human and ecosystem health from chronic exposure to chemical pollution, and considerable effort has been made to identify priority pollutants, understand their toxicological effects, and examine their presence and fate within the environment. Two classes of chemical pollutant that can induce biological effects at extremely low concentrations are pharmaceuticals and steroid hormones. Each has been linked to adverse health effects in humans or wildlife, and each has been detected in surface waters throughout the world, from sources including wastewater treatment plants and agricultural operations.

ISBN: 9781303977510Subjects--Topical Terms:

677245
Environmental science.

Photodegradation of selected endocrine and pharmaceutically active compounds under environmentally relevant conditions -- Processes and products.
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100 1 $a Young, Robert B. $3 1933700
245 1 0 $a Photodegradation of selected endocrine and pharmaceutically active compounds under environmentally relevant conditions -- Processes and products.
300 $a 244 p.
500 $a Source: Dissertation Abstracts International, Volume: 75-10(E), Section: B.
500 $a Adviser: Thomas Borch.
502 $a Thesis (Ph.D.)--Colorado State University, 2014.
506 $a This item must not be sold to any third party vendors.
506 $a This item must not be added to any third party search indexes.
520 $a Within the past few decades, books such as Silent Spring and Our Stolen Future have done much to raise the public's awareness of the threat to human and ecosystem health from chronic exposure to chemical pollution, and considerable effort has been made to identify priority pollutants, understand their toxicological effects, and examine their presence and fate within the environment. Two classes of chemical pollutant that can induce biological effects at extremely low concentrations are pharmaceuticals and steroid hormones. Each has been linked to adverse health effects in humans or wildlife, and each has been detected in surface waters throughout the world, from sources including wastewater treatment plants and agricultural operations.
520 $a Once present in surface waters, pharmaceuticals and steroid hormones are subject to various transformation and removal processes, including biodegradation, photodegradation, and sorption to colloids or sediments. Because biodegradation and sorption are the primary removal processes during wastewater treatment, photodegradation might be especially important in surface waters, at least for those pharmaceuticals and steroid hormones that have survived wastewater treatment. This dissertation examines the photodegradation of selected pharmaceuticals and steroid hormones (androstenedione, testosterone, and lamotrigine) under environmentally relevant conditions, including natural or simulated sunlight, aqueous solutions at different pH, and the presence of dissolved organic matter.
520 $a Chapter 1 of the dissertation provides a brief introduction to surface water pollution and environmental photochemistry.
520 $a Chapter 2 of the dissertation reviews existing literature on the presence of steroid hormones in freshwater ecosystems, their sources, and their potential fate. Chapter 2 compiles information about the physical and chemical properties of selected steroid hormones, and considers how biodegradation, photodegradation, and sorption influence steroid hormone fate in freshwater ecosystems.
520 $a Chapter 3 of the dissertation examines the direct photodegradation of lamotrigine (LTG), an antiepileptic and mood stabilizing drug that has been detected in wastewater, groundwater, surface water and drinking water.
520 $a Chapter 4 of the dissertation compares the direct photodegradation of dilute (<10 mug L-1) aqueous solutions of androstenedione (AD) and testosterone (T), two commonly observed male sex hormones, and evaluates the endocrine-disrupting potential of the resulting solutions. In addition, Chapter 4 examines the effect of dissolved organic matter (DOM) on AD photodegradation.
520 $a Chapter 5 of the dissertation presents broad conclusions from the research described in the dissertation, and suggests future work to advance the understanding of pollutant persistence and environmental photodegradation processes. (Abstract shortened by UMI.).
590 $a School code: 0053.
650 4 $a Environmental science. $3 677245
650 4 $a Geochemistry. $3 539092
650 4 $a Environmental health. $3 543032
690 $a 0768
690 $a 0996
690 $a 0470
710 2 $a Colorado State University. $b Soil and Crop Sciences. $3 1682821
773 0 $t Dissertation Abstracts International $g 75-10B(E).
790 $a 0053
791 $a Ph.D.
792 $a 2014
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3624417