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Physiologically-based pharmacokineti...
Peters, Sheila Annie.

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  • Physiologically-based pharmacokinetic (PBPK) modeling and simulations = principles, methods, and applications in the pharmaceutical industry /
  • Record Type: Electronic resources : Monograph/item
    Title/Author: Physiologically-based pharmacokinetic (PBPK) modeling and simulations/ Sheila Annie Peters.
    Reminder of title: principles, methods, and applications in the pharmaceutical industry /
    remainder title: Physiologically based pharmacokinetic modeling and simulations
    Author: Peters, Sheila Annie.
    Published: Hoboken, N.J. :Wiley, : c2012.,
    Description: 1 online resource (xvii, 430 p.) :ill.
    Notes: Wiley online library (ebook collection)
    [NT 15003449]: Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.
    Subject: Pharmacokinetics - Mathematical models. -
    Online resource: http://onlinelibrary.wiley.com/book/10.1002/9781118140291
    ISBN: 9781118140291 (electronic bk.)
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