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Transactivational activity of the tu...
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Merwin, Jason R.
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Transactivational activity of the tumor suppressor proteinp53 is dependent on thioredoxin reductase activity in mammalian cells.
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書目-電子資源 : Monograph/item
正題名/作者:
Transactivational activity of the tumor suppressor proteinp53 is dependent on thioredoxin reductase activity in mammalian cells./
作者:
Merwin, Jason R.
面頁冊數:
153 p.
附註:
Source: Dissertation Abstracts International, Volume: 64-12, Section: B, page: 5935.
Contained By:
Dissertation Abstracts International64-12B.
標題:
Biology, Molecular. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3115475
Transactivational activity of the tumor suppressor proteinp53 is dependent on thioredoxin reductase activity in mammalian cells.
Merwin, Jason R.
Transactivational activity of the tumor suppressor proteinp53 is dependent on thioredoxin reductase activity in mammalian cells.
- 153 p.
Source: Dissertation Abstracts International, Volume: 64-12, Section: B, page: 5935.
Thesis (Ph.D.)--Oregon State University, 2004.
Reporter gene transactivation by human p53 is inhibited in budding yeast lacking the TRR1 gene encoding thioredoxin reductase. Thioredoxin reductase specifically catalyzes the NADPH-dependent reduction of thioredoxin. Thioredoxin provides a sourSubjects--Topical Terms:
1017719
Biology, Molecular.
Transactivational activity of the tumor suppressor proteinp53 is dependent on thioredoxin reductase activity in mammalian cells.
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Source: Dissertation Abstracts International, Volume: 64-12, Section: B, page: 5935.
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Thesis (Ph.D.)--Oregon State University, 2004.
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In order to test if p53 activity requires an intact thioredoxin system in mammalian cells, dominant-negative and RNAi approaches designed to suppress thioredoxin reductase activity were used in a breast adenocarcinoma cell which contains an endo
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3115475
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