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Garlic (Allium sativum) for horses: ...

Pearson, Wendy.

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Garlic (Allium sativum) for horses: In vitro antibacterial activity and in vivo toxicity.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Garlic (Allium sativum) for horses: In vitro antibacterial activity and in vivo toxicity./
Author:	Pearson, Wendy.
Description:	120 p.
Notes:	Source: Masters Abstracts International, Volume: 42-06, page: 2198.
Contained By:	Masters Abstracts International42-06.
Subject:	Health Sciences, Toxicology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MQ90685
ISBN:	061290685X

Garlic (Allium sativum) for horses: In vitro antibacterial activity and in vivo toxicity.
Pearson, Wendy.

Garlic (Allium sativum) for horses: In vitro antibacterial activity and in vivo toxicity. - 120 p.

Source: Masters Abstracts International, Volume: 42-06, page: 2198.

Thesis (M.Sc.)--University of Guelph (Canada), 2004.

Garlic, commonly used as a supplement in livestock feed, has demonstrated toxic effects in some species. A disk diffusion method was utilized to determine the minimum inhibitory concentration (MIC) of allyl mercaptan against Streptococcus equi in vitro. Subsequently, freeze-dried garlic was offered to 2 horses for 71 days in gradually increasing doses from 0.05 g/kg BW b.i.d. to maximum voluntary intake (0.25 g/kg BW b.i.d.). Jugular blood sampled weekly was analyzed for hematology, biochemistry and Heinz bodies. The in vitro study concluded that allyl mercaptan does not have appreciable antibiotic activity against S. equi as measured by MICs in excess of 8g/L. In vivo, daily garlic in excess of 0.2 g/kg b.i.d. resulted in reduced red blood cell count, total and corpuscular hemoglobin and haptoglobin. There was an increased incidence of Heinz bodies on erythrocytes, erythrocyte size and total and free bilirubin. Recovery was largely complete within 4 weeks.

ISBN: 061290685XSubjects--Topical Terms:

1017752
Health Sciences, Toxicology.

Garlic (Allium sativum) for horses: In vitro antibacterial activity and in vivo toxicity.
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100 1 $a Pearson, Wendy. $3 1933858
245 1 0 $a Garlic (Allium sativum) for horses: In vitro antibacterial activity and in vivo toxicity.
300 $a 120 p.
500 $a Source: Masters Abstracts International, Volume: 42-06, page: 2198.
500 $a Adviser: Michael I. Lindinger.
502 $a Thesis (M.Sc.)--University of Guelph (Canada), 2004.
520 $a Garlic, commonly used as a supplement in livestock feed, has demonstrated toxic effects in some species. A disk diffusion method was utilized to determine the minimum inhibitory concentration (MIC) of allyl mercaptan against Streptococcus equi in vitro. Subsequently, freeze-dried garlic was offered to 2 horses for 71 days in gradually increasing doses from 0.05 g/kg BW b.i.d. to maximum voluntary intake (0.25 g/kg BW b.i.d.). Jugular blood sampled weekly was analyzed for hematology, biochemistry and Heinz bodies. The in vitro study concluded that allyl mercaptan does not have appreciable antibiotic activity against S. equi as measured by MICs in excess of 8g/L. In vivo, daily garlic in excess of 0.2 g/kg b.i.d. resulted in reduced red blood cell count, total and corpuscular hemoglobin and haptoglobin. There was an increased incidence of Heinz bodies on erythrocytes, erythrocyte size and total and free bilirubin. Recovery was largely complete within 4 weeks.
590 $a School code: 0081.
650 4 $a Health Sciences, Toxicology. $3 1017752
650 4 $a Agriculture, Animal Culture and Nutrition. $3 1017857
690 $a 0383
690 $a 0475
710 2 0 $a University of Guelph (Canada). $3 1018650
773 0 $t Masters Abstracts International $g 42-06.
790 1 0 $a Lindinger, Michael I., $e advisor
790 $a 0081
791 $a M.Sc.
792 $a 2004
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MQ90685