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Electrokinetic transport phenomena: ...

Oddy, Michael Huson.

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Electrokinetic transport phenomena: Mobility measurement and electrokinetic instability.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Electrokinetic transport phenomena: Mobility measurement and electrokinetic instability./
Author:	Oddy, Michael Huson.
Description:	152 p.
Notes:	Source: Dissertation Abstracts International, Volume: 66-01, Section: B, page: 0512.
Contained By:	Dissertation Abstracts International66-01B.
Subject:	Engineering, Mechanical. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3162387
ISBN:	9780496964512

Electrokinetic transport phenomena: Mobility measurement and electrokinetic instability.
Oddy, Michael Huson.

Electrokinetic transport phenomena: Mobility measurement and electrokinetic instability. - 152 p.

Source: Dissertation Abstracts International, Volume: 66-01, Section: B, page: 0512.

Thesis (Ph.D.)--Stanford University, 2005.

Miniaturization and integration of traditional bioassay procedures into microfabricated on-chip assay systems, commonly referred to as "Micro Total Analysis" (muTAS) systems, may have a significant impact on the fields of genomics, proteomics, and clinical analysis. These bioanalytical microsystems leverage electroosmosis and electrophoresis for sample transport, mixing, manipulation, and separation. This dissertation addresses the following three topics relevant to such systems: a new diagnostic for measuring the electrophoretic mobility of sub-micron, fluorescently-labeled particles and the electroosmotic mobility of a microchannel; a novel method and device for rapidly stirring micro- and nanoliter volume solutions for microfluidic bioanalytical applications; and a multiple-species electrokinetic instability model.

ISBN: 9780496964512Subjects--Topical Terms:

783786
Engineering, Mechanical.

Electrokinetic transport phenomena: Mobility measurement and electrokinetic instability.
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008 130610s2005 eng d
020 $a 9780496964512
035 $a (UnM)AAI3162387
035 $a AAI3162387
040 $a UnM $c UnM
100 1 $a Oddy, Michael Huson. $3 1916719
245 1 0 $a Electrokinetic transport phenomena: Mobility measurement and electrokinetic instability.
300 $a 152 p.
500 $a Source: Dissertation Abstracts International, Volume: 66-01, Section: B, page: 0512.
500 $a Adviser: Juan G. Santiago.
502 $a Thesis (Ph.D.)--Stanford University, 2005.
520 $a Miniaturization and integration of traditional bioassay procedures into microfabricated on-chip assay systems, commonly referred to as "Micro Total Analysis" (muTAS) systems, may have a significant impact on the fields of genomics, proteomics, and clinical analysis. These bioanalytical microsystems leverage electroosmosis and electrophoresis for sample transport, mixing, manipulation, and separation. This dissertation addresses the following three topics relevant to such systems: a new diagnostic for measuring the electrophoretic mobility of sub-micron, fluorescently-labeled particles and the electroosmotic mobility of a microchannel; a novel method and device for rapidly stirring micro- and nanoliter volume solutions for microfluidic bioanalytical applications; and a multiple-species electrokinetic instability model.
520 $a Accurate measurement of the electrophoretic particle mobility and the electroosmotic mobility of microchannel surfaces is crucial to understanding the stability of colloidal suspensions, obtaining particle tracking-based velocimetry measurements of electroosmotic flow fields, and the quantification of electrokinetic bioanalytical device performance. A method for determining these mobilities from alternating and direct current electrokinetic particle tracking measurements is presented.
520 $a The ability to rapidly mix fluids at low Reynolds numbers is important to the functionality of many bioanalytical, microfluidic devices. We present an electrokinetic process for rapidly stirring microflow streams by initiating an electrokinetic flow instability. The design, fabrication and performance analysis of two micromixing devices capable of rapidly stirring two low Reynolds number fluid streams are presented. Electroosmotic and electrophoretic transport in the presence of conductivity mismatches between reagent streams and the background electrolytes, can lead to an unstable flow field generating significant sample dispersion. In the multiple-species electrokinetic instability model, we consider a high aspect ratio microchannel geometry, a conductivity gradient orthogonal to the applied electric field, and a four-species chemistry model. A linear stability analysis of the depth-averaged governing equations shows unstable eigenmodes for conductivity ratios as close to unity as 1.01. Experiments and full nonlinear simulations of the governing equations were conducted for a conductivity ratio of 1.05. Images of the disturbance dye field from the nonlinear simulations show good qualitative and quantitative agreement with experiment. Species electromigration is shown to a have significant influence on the development of the conductivity field and instability dynamics in multi-ion configurations.
590 $a School code: 0212.
650 4 $a Engineering, Mechanical. $3 783786
650 4 $a Physics, Fluid and Plasma. $3 1018402
690 $a 0548
690 $a 0759
710 2 0 $a Stanford University. $3 754827
773 0 $t Dissertation Abstracts International $g 66-01B.
790 1 0 $a Santiago, Juan G., $e advisor
790 $a 0212
791 $a Ph.D.
792 $a 2005
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3162387