東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁 到查詢結果 [ null ]

切換: 標籤 | MARC模式 | ISBD

Potential influences of oral contrac...

Almstedt Shoepe, Hawley Chase.

FindBook

Google Book

Amazon

博客來

Potential influences of oral contraceptive use and physical activity on bone health: A one-year prospective study in young women.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Potential influences of oral contraceptive use and physical activity on bone health: A one-year prospective study in young women./
作者:	Almstedt Shoepe, Hawley Chase.
面頁冊數:	108 p.
附註:	Source: Dissertation Abstracts International, Volume: 66-03, Section: B, page: 1432.
Contained By:	Dissertation Abstracts International66-03B.
標題:	Health Sciences, Recreation. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3169748
ISBN:	9780542058349

Potential influences of oral contraceptive use and physical activity on bone health: A one-year prospective study in young women.
Almstedt Shoepe, Hawley Chase.

Potential influences of oral contraceptive use and physical activity on bone health: A one-year prospective study in young women. - 108 p.

Source: Dissertation Abstracts International, Volume: 66-03, Section: B, page: 1432.

Thesis (Ph.D.)--Oregon State University, 2005.

Osteoporosis is a skeletal disease affecting 44 million Americans. A primary strategy to prevent osteoporosis is to develop a high peak bone mass in youth. Oral Contraceptives (OCs) alter hormones in women and could affect bone mass development. The interaction between OCs and skeletal mineralization is poorly understood. Purpose. Our aims were to (1) compare bone mineral density (BMD) of young women who had a history of OC use with regularly menstruating controls, (2) compare changes in BMD in controls, women who initiate OC use, and those who have a history of use, and (3) to evaluate predictive capabilities of physical activity and years of oral contraceptives use on changes in BMD. Methods. We recruited women, 18 to 25 years of age, with a history of OC use and controls. BMD at the hip, whole-body, and spine (AP, g/cm2 and width-adjusted lateral, g/cm 3) was measured by dual-energy x-ray absorptiometry. Physical activity (METs) was measured via questionnaire and grip strength was evaluated using an isometric dynamometer. Results. Groups were similar in body mass index (BMI), fat mass, grip strength, calcium intake and physical activity but controls were slightly older than OC users. In analysis of covariance (ANCOVA), controlling for age and BMI, controls had significantly greater BMD than OC users at baseline at the AP and lateral spine, hip, and whole-body (p < 0.05). By ANCOVA (covariates = age at baseline, change in weight), oral contraceptive users had greater bone loss at L3 in the lateral view than controls whereas, controls had greater increases in L3 volumetric BMD, BMD of the total hip, and whole body than OC users (p < 0.05). Stepwise regression results did not reveal years of oral contraceptive use, grip strength, or METs to be a significant predictor of changes in BMD at any site. Conclusions. We conclude that, in the cross-sectional analysis, oral contraceptive use by young women may compromise bone health during a time when mineral is still accruing. In the prospective analysis, regularly menstruating controls had greater BMD accrual or less bone loss over a 12-month time period than women with a history of oral contraceptive use.

ISBN: 9780542058349Subjects--Topical Terms:

1018003
Health Sciences, Recreation.

Potential influences of oral contraceptive use and physical activity on bone health: A one-year prospective study in young women.
LDR:03139nmm 2200277 4500 001 1826079
005 20061218074236.5
008 130610s2005 eng d
020 $a 9780542058349
035 $a (UnM)AAI3169748
035 $a AAI3169748
040 $a UnM $c UnM
100 1 $a Almstedt Shoepe, Hawley Chase. $3 1915051
245 1 0 $a Potential influences of oral contraceptive use and physical activity on bone health: A one-year prospective study in young women.
300 $a 108 p.
500 $a Source: Dissertation Abstracts International, Volume: 66-03, Section: B, page: 1432.
500 $a Adviser: Christine M. Snow.
502 $a Thesis (Ph.D.)--Oregon State University, 2005.
520 $a Osteoporosis is a skeletal disease affecting 44 million Americans. A primary strategy to prevent osteoporosis is to develop a high peak bone mass in youth. Oral Contraceptives (OCs) alter hormones in women and could affect bone mass development. The interaction between OCs and skeletal mineralization is poorly understood. Purpose. Our aims were to (1) compare bone mineral density (BMD) of young women who had a history of OC use with regularly menstruating controls, (2) compare changes in BMD in controls, women who initiate OC use, and those who have a history of use, and (3) to evaluate predictive capabilities of physical activity and years of oral contraceptives use on changes in BMD. Methods. We recruited women, 18 to 25 years of age, with a history of OC use and controls. BMD at the hip, whole-body, and spine (AP, g/cm2 and width-adjusted lateral, g/cm 3) was measured by dual-energy x-ray absorptiometry. Physical activity (METs) was measured via questionnaire and grip strength was evaluated using an isometric dynamometer. Results. Groups were similar in body mass index (BMI), fat mass, grip strength, calcium intake and physical activity but controls were slightly older than OC users. In analysis of covariance (ANCOVA), controlling for age and BMI, controls had significantly greater BMD than OC users at baseline at the AP and lateral spine, hip, and whole-body (p < 0.05). By ANCOVA (covariates = age at baseline, change in weight), oral contraceptive users had greater bone loss at L3 in the lateral view than controls whereas, controls had greater increases in L3 volumetric BMD, BMD of the total hip, and whole body than OC users (p < 0.05). Stepwise regression results did not reveal years of oral contraceptive use, grip strength, or METs to be a significant predictor of changes in BMD at any site. Conclusions. We conclude that, in the cross-sectional analysis, oral contraceptive use by young women may compromise bone health during a time when mineral is still accruing. In the prospective analysis, regularly menstruating controls had greater BMD accrual or less bone loss over a 12-month time period than women with a history of oral contraceptive use.
590 $a School code: 0172.
650 4 $a Health Sciences, Recreation. $3 1018003
650 4 $a Biology, Animal Physiology. $3 1017835
690 $a 0575
690 $a 0433
710 2 0 $a Oregon State University. $3 625720
773 0 $t Dissertation Abstracts International $g 66-03B.
790 1 0 $a Snow, Christine M., $e advisor
790 $a 0172
791 $a Ph.D.
792 $a 2005
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3169748